Protein: TET1
Methylcytosine dioxygenase TET1 (EC 1.14.11.80) (CXXC-type zinc finger protein 6) (Leukemia-associated protein with a CXXC domain) (Ten-eleven translocation 1 gene protein)

Gene: TET1
Organism: Homo sapiens
Interactions: 36
UniProt ID: Q8NFU7

Gene Ontology (top 5):
GO:0000122 - negative regulation of transcription by RNA polymerase II
GO:0000978 - RNA polymerase II cis-regulatory region sequence-specific DNA binding
GO:0001826 - inner cell mass cell differentiation
GO:0003677 - DNA binding
GO:0005506 - iron ion binding

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

185869

OGT1
UDP-N-acetylglucosamine--peptide N-acetylglucosaminyltransferase 110 kDa subunit

3

5

Small-scale

0.650

High

1161329

HIF1A
Hypoxia-inducible factor 1-alpha

2

1

Small-scale

0.584

High

1339524

DCAF1
DDB1- and CUL4-associated factor 1

2

4

Small-scale

0.584

High

691263

1433T
14-3-3 protein theta

1

10

High-throughput

0.536

High

966643

1433G
14-3-3 protein gamma

1

10

High-throughput

0.536

High

971800

1433E
14-3-3 protein epsilon

1

1

High-throughput

0.536

High

1163076

H2B2E
Histone H2B type 2-E

1

1

High-throughput

0.536

High

1339515

PSPC1
Paraspeckle component 1

1

5

High-throughput

0.536

High

682552

S100P
Protein S100-P

1

0

High-throughput

0.513

High

352193

MBD3
Methyl-CpG-binding domain protein 3

1

2

Small-scale

0.501

High

1049583

1433F
14-3-3 protein eta

1

10

High-throughput

0.489

High

143128

NFIB
Nuclear factor 1 B-type

1

10

High-throughput

0.479

High

246780

KDM1A
Lysine-specific histone demethylase 1A

1

5

High-throughput

0.479

High

408999

G3P
Glyceraldehyde-3-phosphate dehydrogenase

1

1

High-throughput

0.479

High

474138

NFIC
Nuclear factor 1 C-type

1

10

High-throughput

0.479

High

538440

EGR2
E3 SUMO-protein ligase EGR2

1

3

High-throughput

0.479

High

1087879

NFIA
Nuclear factor 1 A-type

1

10

High-throughput

0.479

High

1109910

HDAC1
Histone deacetylase 1

1

4

High-throughput

0.479

High

1113751

CUL3
Cullin-3

1

4

High-throughput

0.479

High

1114946

CUL4A
Cullin-4A

1

4

Small-scale

0.479

High

1115307

CUL4B
Cullin-4B

1

4

Small-scale

0.479

High

1120631

DAG1
Dystroglycan 1

1

1

High-throughput

0.479

High

1157824

DDB1
DNA damage-binding protein 1

1

2

Small-scale

0.479

High

1276508

PARPT
Protein mono-ADP-ribosyltransferase TIPARP

1

1

High-throughput

0.479

High

1339519

UHRF1
E3 ubiquitin-protein ligase UHRF1

1

1

Small-scale

0.479

High

1339520

EPAS1
Endothelial PAS domain-containing protein 1

1

1

Small-scale

0.479

High

1339523

RCOR1
REST corepressor 1

1

1

High-throughput

0.479

High

862309

YAP1
Transcriptional coactivator YAP1

1

0

High-throughput

0.458

High

869065

TISD
mRNA decay activator protein ZFP36L2

1

0

High-throughput

0.458

High

1339516

SMG7
Nonsense-mediated mRNA decay factor SMG7

1

0

High-throughput

0.458

High

1339517

PF21A
PHD finger protein 21A

1

0

High-throughput

0.458

High

1339521

RPA49
DNA-directed RNA polymerase I subunit RPA49

1

0

High-throughput

0.458

High

1339518

SIN3A
Paired amphipathic helix protein Sin3a

1

3

Small-scale

0.445

High

1063452

GOGA2
Golgin subfamily A member 2

1

2

High-throughput

0.437

High

1227091

A16L1
Autophagy-related protein 16-1

1

1

High-throughput

0.407

High

1339522

OCAD1
OCIA domain-containing protein 1

1

0

High-throughput

0.249

Low


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Last updated: 11Aug2025