HitPredict

Interactor 1: CTRO (O14578)
Citron Rho-interacting kinase (CRIK) (EC 2.7.11.1) (Serine/threonine-protein kinase 21)
Gene: CIT

Interactor 2: EIF3A (Q14152)
Eukaryotic translation initiation factor 3 subunit A (eIF3a) (Eukaryotic translation initiation factor 3 subunit 10) (eIF-3-theta) (eIF3 p167) (eIF3 p180) (eIF3 p185)
Gene: EIF3A

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	31586073
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005829 - cytosol GO:0016020 - membrane
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 2027 Hs			1 1382
+	Hs
		148460 CTRO_HUMAN (1-2027): 0: 1212: 100.00		MYH9_HUMAN (55-1098): 6.44e-45: 180: 9.65
+	Hs
		148769 CTRO_HUMAN (1-2027): 0: 1212: 100.00		GOGA4_HUMAN (70-1382): 7.95e-38: 157: 9.14
+	Hs
		148461 CTRO_HUMAN (1-2027): 0: 1212: 100.00		MYH10_HUMAN (46-929): 1.09e-34: 147: 10.53
+	Hs
		148466 CTRO_HUMAN (1-2027): 0: 1212: 100.00		MYH11_HUMAN (79-823): 1.69e-23: 110: 11.10
+	Hs
		148841 CTRO_HUMAN (1-2027): 0: 1212: 100.00		PLEC_HUMAN (497-1343): 1.73e-18: 94.5: 13.97
+	Hs
		148991 CTRO_HUMAN (1-2027): 0: 1212: 100.00		MYH14_HUMAN (488-1381): 1.41e-12: 75.1: 9.26
+	Hs
		148941 CTRO_HUMAN (1-2027): 0: 1212: 100.00		NIPBL_HUMAN (599-1299): 2.68e-11: 71.1: 13.13
+	Hs
		148359 CTRO_HUMAN (1-2027): 0: 1212: 100.00		DESP_HUMAN (478-1060): 3.57e-11: 70.4: 13.18
+	Hs
		149126 CTRO_HUMAN (1-2027): 0: 1212: 100.00		MY18A_HUMAN (532-955): 1.34e-09: 65.3: 16.18
+	Rn
		1092818 AKT3_RAT (44-404): 7.24e-122: 395: 31.37		EIF3A_RAT (1-1382): 1.04e-107: 374: 88.36
+	Hs
		116964 SGK1_HUMAN (59-407): 8.42e-121: 390: 31.37		MYH1_HUMAN (83-1022): 3.5e-18: 93.2: 10.72
+	Hs
		117013 SGK1_HUMAN (59-407): 8.42e-121: 390: 31.37		MYH14_HUMAN (488-1381): 1.41e-12: 75.1: 9.26
+	Hs
		725079 ST38L_HUMAN (74-430): 6.61e-69: 242: 35.79		MYH9_HUMAN (55-1098): 6.44e-45: 180: 9.65
+	Hs
		1154090 ST38L_HUMAN (74-430): 6.61e-69: 242: 35.79		NIPBL_HUMAN (599-1299): 2.68e-11: 71.1: 13.13
+	Hs
		1069616 STK38_HUMAN (87-430): 1.1e-68: 241: 36.29		NIPBL_HUMAN (599-1299): 2.68e-11: 71.1: 13.13
+	Hs
		724810 ROCK1_HUMAN (1051-1566): 8.4e-21: 102: 10.08		MYH9_HUMAN (55-1098): 6.44e-45: 180: 9.65
+	Rn
		222476 MRCKA_RAT (536-1070): 1.62e-33: 144: 11.97		MRCKB_RAT (532-1059): 2.84e-15: 83.9: 12.81
+	Rn
		1186812 MRCKB_RAT (566-1070): 2.51e-33: 143: 12.74		MRCKB_RAT (532-1059): 2.84e-15: 83.9: 12.81
+	Hs
		1137917 MRCKA_HUMAN (536-1061): 4.38e-32: 139: 11.82		MRCKB_HUMAN (610-1132): 1.14e-14: 82: 10.96
+	Hs
		1268126 MRCKB_HUMAN (569-1070): 4.13e-33: 143: 12.04		MY18A_HUMAN (532-955): 1.34e-09: 65.3: 16.18