Protein: INCE
Inner centromere protein

Gene: INCE, INCENP
Organism: Homo sapiens
Interactions: 82
UniProt ID: Q9NQS7

Gene Ontology (top 5):
GO:0000278 - mitotic cell cycle
GO:0000281 - mitotic cytokinesis
GO:0000775 - chromosome, centromeric region
GO:0000776 - kinetochore
GO:0000800 - lateral element

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

1391787

AURKB
Aurora kinase B

27

20

Small-scale

0.992

High

1200152

BOREA
Borealin

8

6

Small-scale

0.975

High

1447224

AURKC
Aurora kinase C

7

20

Small-scale

0.969

High

170368

AURKA
Aurora kinase A

4

20

Small-scale

0.926

High

188719

BIRC5
Baculoviral IAP repeat-containing protein 5

10

10

Small-scale

0.759

High

1095465

AAPK1
5'-AMP-activated protein kinase catalytic subunit alpha-1

1

14

High-throughput

0.691

High

853416

CBX5
Chromobox protein homolog 5

3

7

Small-scale

0.685

High

998841

H31
Histone H3.1

3

17

High-throughput

0.640

High

1163227

H2B2E
Histone H2B type 2-E

2

20

High-throughput

0.621

High

157891

CTRO
Citron Rho-interacting kinase

1

20

High-throughput

0.618

High

193630

PDPK1
3-phosphoinositide-dependent protein kinase 1

1

9

High-throughput

0.618

High

244284

NUAK1
NUAK family SNF1-like kinase 1

1

11

High-throughput

0.618

High

443530

CDK1
Cyclin-dependent kinase 1

1

16

Small-scale

0.618

High

373233

MYC
Myc proto-oncogene protein

2

17

High-throughput

0.584

High

981119

H2B1C
Histone H2B type 1-C/E/F/G/I

2

20

High-throughput

0.584

High

1097581

CBX3
Chromobox protein homolog 3

2

7

Small-scale

0.584

High

1447216

ANLN
Anillin

2

7

High-throughput

0.584

High

249011

EVI5
Ecotropic viral integration site 5 protein homolog

1

2

Small-scale

0.561

High

682624

S100P
Protein S100-P

1

18

High-throughput

0.536

High

1013108

HMGN5
High mobility group nucleosome-binding domain-containing protein 5

1

2

High-throughput

0.536

High

1095946

EI2BE
Translation initiation factor eIF2B subunit epsilon

1

1

High-throughput

0.536

High

1417961

SHAN3
SH3 and multiple ankyrin repeat domains protein 3

1

16

High-throughput

0.536

High

1447223

PHF8
Histone lysine demethylase PHF8

1

2

High-throughput

0.536

High

502143

H2AZ
Histone H2A.Z

1

7

Small-scale

0.527

High

946889

H2B1D
Histone H2B type 1-D

1

20

High-throughput

0.515

High

299391

FLOT1
Flotillin-1

1

8

Small-scale

0.512

High

1258958

H32
Histone H3.2

1

17

Small-scale

0.501

High

1109398

PIN1
Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1

1

0

Small-scale

0.480

High

191112

RPA34
DNA-directed RNA polymerase I subunit RPA34

1

10

High-throughput

0.479

High

223356

PRC1
Protein regulator of cytokinesis 1

1

17

High-throughput

0.479

High

248357

HBP1
HMG box-containing protein 1

1

5

High-throughput

0.479

High

260497

BRD4
Bromodomain-containing protein 4

1

12

High-throughput

0.479

High

331347

KI20A
Kinesin-like protein KIF20A

1

20

High-throughput

0.479

High

363900

EGFR
Epidermal growth factor receptor

1

16

High-throughput

0.479

High

386265

LMNA
Prelamin-A/C [Cleaved into: Lamin-A/C

1

15

High-throughput

0.479

High

414682

P53
Cellular tumor antigen p53

1

8

High-throughput

0.479

High

463786

LYN
Tyrosine-protein kinase Lyn

1

15

High-throughput

0.479

High

487786

PARP1
Poly [ADP-ribose] polymerase 1

1

12

High-throughput

0.479

High

589779

RFA2
Replication protein A 32 kDa subunit

1

11

High-throughput

0.479

High

697263

APEX1
DNA repair nuclease/redox regulator APEX1

1

2

High-throughput

0.479

High

883699

CENPA
Histone H3-like centromeric protein A

1

17

High-throughput

0.479

High

986748

PPIA
Peptidyl-prolyl cis-trans isomerase A

1

6

High-throughput

0.479

High

1014210

CBX1
Chromobox protein homolog 1

1

7

Small-scale

0.479

High

1017234

H33
Histone H3.3

1

17

High-throughput

0.479

High

1033252

EWS
RNA-binding protein EWS

1

8

High-throughput

0.479

High

1035931

KIF23
Kinesin-like protein KIF23

1

17

High-throughput

0.479

High

1058303

C1QBP
Complement component 1 Q subcomponent-binding protein, mitochondrial

1

2

High-throughput

0.479

High

1107242

BIRC3
Baculoviral IAP repeat-containing protein 3

1

11

High-throughput

0.479

High

1140911

KIF14
Kinesin-like protein KIF14

1

16

High-throughput

0.479

High

1145537

RBBP5
Retinoblastoma-binding protein 5

1

16

High-throughput

0.479

High

1161691

IF16
Gamma-interferon-inducible protein 16

1

1

High-throughput

0.479

High

1276831

PARPT
Protein mono-ADP-ribosyltransferase TIPARP

1

10

High-throughput

0.479

High

1281620

SLN11
Schlafen family member 11

1

5

High-throughput

0.479

High

1313451

SMC5
Structural maintenance of chromosomes protein 5

1

20

High-throughput

0.479

High

1314432

SLX4
Structure-specific endonuclease subunit SLX4

1

12

High-throughput

0.479

High

1328968

ZBTB2
Zinc finger and BTB domain-containing protein 2

1

7

High-throughput

0.479

High

1385876

CHM4C
Charged multivesicular body protein 4c

1

11

High-throughput

0.479

High

1429854

TOLIP
Toll-interacting protein

1

1

High-throughput

0.479

High

1433085

CHM4B
Charged multivesicular body protein 4b

1

11

High-throughput

0.479

High

1436493

ECT2
Protein ECT2

1

20

High-throughput

0.479

High

1447217

SIR7
NAD-dependent protein deacetylase sirtuin-7

1

7

High-throughput

0.479

High

1447219

TE2IP
Telomeric repeat-binding factor 2-interacting protein 1

1

1

High-throughput

0.479

High

1447221

ZRAN1
Ubiquitin thioesterase ZRANB1

1

17

High-throughput

0.479

High

1447225

ASF1A
Histone chaperone ASF1A

1

1

High-throughput

0.479

High

1447226

ZN330
Zinc finger protein 330

1

1

High-throughput

0.479

High

1204397

SGO1
Shugoshin 1

1

0

Small-scale

0.458

High

1252985

BAKOR
Beclin 1-associated autophagy-related key regulator

1

0

High-throughput

0.458

High

430398

JUN
Transcription factor Jun

1

9

High-throughput

0.445

High

860966

RS10
Small ribosomal subunit protein eS10

1

9

High-throughput

0.445

High

1112189

KRR1
KRR1 small subunit processome component homolog

1

1

High-throughput

0.445

High

1239951

CAVN1
Caveolae-associated protein 1

1

1

High-throughput

0.445

High

1277246

POGZ
Pogo transposable element with ZNF domain

1

2

Small-scale

0.445

High

107341

F8VWT9
HECT domain E3 ubiquitin protein ligase 4

1

10

High-throughput

0.437

High

1071193

ARL16
ADP-ribosylation factor-like protein 16

1

11

High-throughput

0.437

High

1255678

TRI67
Tripartite motif-containing protein 67

1

20

High-throughput

0.437

High

1327216

FBXL6
F-box/LRR-repeat protein 6

1

4

High-throughput

0.437

High

1433975

PKHA4
Pleckstrin homology domain-containing family A member 4

1

20

High-throughput

0.437

High

1447220

HECW2
E3 ubiquitin-protein ligase HECW2

1

8

High-throughput

0.437

High

1447222

HECD1
E3 ubiquitin-protein ligase HECTD1

1

13

High-throughput

0.437

High

1447227

HECD4
Probable E3 ubiquitin-protein ligase HECTD4

1

10

High-throughput

0.437

High

1447218

SLX9
Ribosome biogenesis protein SLX9 homolog

1

0

Small-scale

0.249

Low

1312863

GPAM1
GPALPP motifs-containing protein 1

1

0

High-throughput

0.232

Low


Service provided by Combinatics, Japan

Last updated: 11Aug2025