Interactor 1: RIPK3 (Q9Y572)
Receptor-interacting serine/threonine-protein kinase 3 (EC 2.7.11.1) (RIP-like protein kinase 3) (Receptor-interacting protein 3) (RIP-3)
Gene: RIPK3
Interactor 2: RIPK3 (Q9Y572)
Receptor-interacting serine/threonine-protein kinase 3 (EC 2.7.11.1) (RIP-like protein kinase 3) (Receptor-interacting protein 3) (RIP-3)
Gene: RIPK3
Species: Homo sapiens
Source: intact
Category: Small-scale
Confidence: High
| Method score | Annotation score | Interaction score |
|---|---|---|
| 0.81 | 1.00 | 0.900 |
The method score is based on:
| Property | Details |
|---|---|
| Experiments | 27045108, 19524513, 14743216, 22817896 |
| Identification Methods | enzymatic study, protein kinase assay, tandem affinity purification, molecular sieving, electron microscopy, fluorescence technology, circular dichroism |
| Interaction Type | direct interaction, phosphorylation reaction, physical association |
The annotation score is based on:
| Property | Details |
|---|---|
| Interacting Pfam domains | Pkinase~Pkinase, RHIM~RHIM |
| Common GO terms | GO:0001914 - regulation of T cell mediated cytotoxicity GO:0002819 - regulation of adaptive immune response GO:0003713 - transcription coactivator activity GO:0004672 - protein kinase activity GO:0004674 - protein serine/threonine kinase activity and 34 others more... |
| Homologous interactions | 18 |
Homologous interactions
Color coding for hit scores 
Service provided by Combinatics, Japan
Last updated: 11Aug2025