HitPredict

Interactor 1: CTDS2 (O14595)
Carboxy-terminal domain RNA polymerase II polypeptide A small phosphatase 2 (EC 3.1.3.16) (Nuclear LIM interactor-interacting factor 2) (NLI-interacting factor 2) (Protein OS-4) (Small C-terminal domain phosphatase 2) (Small CTD phosphatase 2) (SCP2)
Gene: CTDSP2

Interactor 2: SMAD1 (Q15797)
Mothers against decapentaplegic homolog 1 (MAD homolog 1) (Mothers against DPP homolog 1) (JV4-1) (Mad-related protein 1) (SMAD family member 1) (SMAD 1) (Smad1) (hSMAD1) (Transforming growth factor-beta-signaling protein 1) (BSP-1)
Gene: SMAD1

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	16882717
Identification Methods	anti tag coimmunoprecipitation
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005654 - nucleoplasm GO:0046872 - metal ion binding
Homologous interactions	6

Homologous interactions

Color coding for hit scores

	1 271 Hs			1 465
+	Hs
		1078756 CTDS1_HUMAN (1-269): 1.3e-101: 298: 60.00		SMAD1_HUMAN (1-465): 0: 658: 100.00
+	Hs
		171217 CTDSL_HUMAN (1-267): 2.28e-101: 298: 62.50		SMAD1_HUMAN (1-465): 0: 658: 100.00
+	Hs
		1078653 CTDS1_HUMAN (1-269): 1.3e-101: 298: 60.00		SMAD2_HUMAN (3-465): 0: 541: 55.14
+	Hs
		171216 CTDSL_HUMAN (1-267): 2.28e-101: 298: 62.50		SMAD2_HUMAN (3-465): 0: 541: 55.14
+	Dm
		785495 CNEP1_DROME (71-268): 2.97e-70: 218: 35.38		MAD_DROME (2-465): 0: 594: 72.85
+	Hs
		1035519 UBCP1_HUMAN (50-268): 1.2e-43: 152: 14.29		SMAD4_HUMAN (13-454): 1.6e-150: 441: 34.28