HitPredict

Interactor 1: GOSR2 (O14653)
Golgi SNAP receptor complex member 2 (27 kDa Golgi SNARE protein) (Membrin)
Gene: GOSR2

Interactor 2: SNAA (P54920)
Alpha-soluble NSF attachment protein (SNAP-alpha) (N-ethylmaleimide-sensitive factor attachment protein alpha)
Gene: NAPA

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.65	0.60	0.628

Property	Details
Experiments	30833792, 35271311
Identification Methods	affinity chromatography technology, pull down, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0000149 - SNARE binding GO:0005829 - cytosol GO:0006891 - intra-Golgi vesicle-mediated transport GO:0016020 - membrane
Homologous interactions	11

Homologous interactions

Color coding for hit scores

	1 212 Hs			1 295
+	Hs
		873571 VTI1A_HUMAN (2-210): 3.39e-52: 169: 11.96		SNAA_HUMAN (1-295): 2.13e-113: 330: 100.00
+	Dm
		1095583 GOSR2_DROME (1-211): 5.02e-53: 171: 41.12		SNAP_DROME (5-295): 7.84e-105: 308: 61.51
+	Hs
		873593 VTI1B_HUMAN (2-190): 7.6e-44: 148: 14.36		SNAA_HUMAN (1-295): 2.13e-113: 330: 100.00
+	Dm
		1095589 Q9W0N6_DROME (1-212): 7.2e-45: 150: 17.89		SNAP_DROME (5-295): 7.84e-105: 308: 61.51
+	Sc
		696593 VTI1_YEAST (3-194): 1.99e-36: 128: 10.55		SEC17_YEAST (8-294): 4.63e-88: 266: 34.48
+	Hs
		1284294 VTI1A_HUMAN (2-210): 3.39e-52: 169: 11.96		SNAG_HUMAN (4-265): 6.75e-68: 215: 23.40
+	Hs
		1306213 VTI1B_HUMAN (2-190): 7.6e-44: 148: 14.36		SNAG_HUMAN (4-265): 6.75e-68: 215: 23.40
+	Dm
		1353746 GOSR2_DROME (1-211): 5.02e-53: 171: 41.12		Q9U6R9_DROME (4-265): 3.84e-58: 190: 18.49
+	Dm
		1366625 GOSR2_DROME (1-211): 5.02e-53: 171: 41.12		Q9VH25_DROME (18-265): 1.8e-53: 177: 17.53
+	Dm
		1353753 Q9W0N6_DROME (1-212): 7.2e-45: 150: 17.89		Q9U6R9_DROME (4-265): 3.84e-58: 190: 18.49
+	Dm
		1366630 Q9W0N6_DROME (1-212): 7.2e-45: 150: 17.89		Q9VH25_DROME (18-265): 1.8e-53: 177: 17.53