HitPredict

Interactor 1: NDC80 (O14777)
Kinetochore protein NDC80 homolog (Highly expressed in cancer protein) (Kinetochore protein Hec1) (HsHec1) (Kinetochore-associated protein 2) (Retinoblastoma-associated protein HEC)
Gene: NDC80

Interactor 2: ASPP2 (Q13625)
Apoptosis-stimulating of p53 protein 2 (Bcl2-binding protein) (Bbp) (Renal carcinoma antigen NY-REN-51) (Tumor suppressor p53-binding protein 2) (53BP2) (p53-binding protein 2) (p53BP2)
Gene: TP53BP2

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.74	0.60	0.669

Property	Details
Experiments	25416956, 32296183, 34079125
Identification Methods	two hybrid, proximity labelling technology, two hybrid prey pooling approach, two hybrid array, validated two hybrid
Interaction Type	direct interaction, physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005654 - nucleoplasm GO:0005829 - cytosol
Homologous interactions	13

Homologous interactions

Color coding for hit scores

	1 642 Hs			1 1128
+	Hs
		154951 NDC80_HUMAN (1-642): 1.46e-79: 266: 100.00		Q05BL1_HUMAN (90-1128): 2.47e-152: 484: 99.90
+	Hs
		155080 NDC80_HUMAN (1-642): 1.46e-79: 266: 100.00		ASPP1_HUMAN (1-1128): 4.45e-135: 439: 45.38
+	Hs
		154994 NDC80_HUMAN (1-642): 1.46e-79: 266: 100.00		KANK2_HUMAN (303-1049): 2.35e-63: 234: 16.00
+	Hs
		1127316 TGO1_HUMAN (195-642): 2.07e-29: 127: 15.45		Q9H4D1_HUMAN (573-1024): 4.3e-26: 117: 11.58
+	Hs
		883527 TGO1_HUMAN (195-642): 2.07e-29: 127: 15.45		RIPK4_HUMAN (863-1024): 1.42e-25: 116: 19.63
+	Hs
		167011 UACA_HUMAN (191-641): 1.51e-30: 130: 13.88		ANR28_HUMAN (771-1049): 2.48e-23: 109: 13.78
+	Hs
		161444 UACA_HUMAN (191-641): 1.51e-30: 130: 13.88		MYPT1_HUMAN (957-1059): 1.81e-16: 87.2: 36.89
+	Hs
		161319 MYH9_HUMAN (181-636): 8.68e-18: 90.2: 9.50		MYPT1_HUMAN (957-1059): 1.81e-16: 87.2: 36.89
+	Hs
		161423 MY18A_HUMAN (210-628): 6.72e-15: 80.8: 14.45		MYPT1_HUMAN (957-1059): 1.81e-16: 87.2: 36.89
+	Hs
		161462 MYO5C_HUMAN (194-519): 6.56e-13: 74.5: 9.71		MYPT1_HUMAN (957-1059): 1.81e-16: 87.2: 36.89
+	Hs
		225128 MYH9_HUMAN (181-636): 8.68e-18: 90.2: 9.50		MYPT2_HUMAN (947-1035): 1.24e-11: 71.4: 33.71
+	Hs
		225152 MY18A_HUMAN (210-628): 6.72e-15: 80.8: 14.45		MYPT2_HUMAN (947-1035): 1.24e-11: 71.4: 33.71
+	Hs
		254502 ROCK2_HUMAN (270-607): 5.3e-09: 61.5: 14.29		ANR49_HUMAN (906-1000): 8.85e-19: 88.7: 30.53