HitPredict

Interactor 1: TNPO2 (O14787)
Transportin-2 (Karyopherin beta-2b)
Gene: TNPO2

Interactor 2: PD1L1 (Q9NZQ7)
Programmed cell death 1 ligand 1 (PD-L1) (PDCD1 ligand 1) (Programmed death ligand 1) (hPD-L1) (B7 homolog 1) (B7-H1) (CD antigen CD274)
Gene: CD274

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.71	0.50	0.599

Property	Details
Experiments	26186194, 28514442, 33961781
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	-
Homologous interactions	18

Homologous interactions

Color coding for hit scores

	1 897 Hs			1 290
+	Hs
		1117742 Q4LE60_HUMAN (1-897): 0: 671: 98.89		PD1L1_HUMAN (1-290): 1.08e-62: 201: 100.00
+	Hs
		1273232 TNPO1_HUMAN (2-897): 0: 625: 84.39		PD1L1_HUMAN (1-290): 1.08e-62: 201: 100.00
+	Hs
		1117739 Q4LE60_HUMAN (1-897): 0: 671: 98.89		VSIG2_HUMAN (3-270): 3.76e-40: 144: 15.11
+	Hs
		155590 TNPO2_HUMAN (1-897): 0: 644: 100.00		BTNL9_HUMAN (14-289): 1.23e-48: 171: 14.44
+	Hs
		1166522 TNPO1_HUMAN (2-897): 0: 625: 84.39		BTNL9_HUMAN (14-289): 1.23e-48: 171: 14.44
+	Hs
		155624 TNPO2_HUMAN (1-897): 0: 644: 100.00		VSIG2_HUMAN (3-270): 3.76e-40: 144: 15.11
+	Hs
		1273203 TNPO1_HUMAN (2-897): 0: 625: 84.39		VSIG2_HUMAN (3-270): 3.76e-40: 144: 15.11
+	Hs
		155541 TNPO2_HUMAN (1-897): 0: 644: 100.00		CD80_HUMAN (28-259): 6.01e-30: 116: 21.07
+	Hs
		874604 XPO2_HUMAN (3-896): 5.07e-90: 308: 13.52		PD1L1_HUMAN (1-290): 1.08e-62: 201: 100.00
+	Hs
		178283 IPO8_HUMAN (10-847): 3.45e-88: 304: 14.44		PD1L1_HUMAN (1-290): 1.08e-62: 201: 100.00
+	Hs
		1060948 IMB1_HUMAN (11-871): 1.22e-86: 297: 17.83		PD1L1_HUMAN (1-290): 1.08e-62: 201: 100.00
+	Hs
		312409 IPO7_HUMAN (11-850): 2.74e-78: 277: 13.25		PD1L1_HUMAN (1-290): 1.08e-62: 201: 100.00
+	Hs
		178195 IPO8_HUMAN (10-847): 3.45e-88: 304: 14.44		BTNL9_HUMAN (14-289): 1.23e-48: 171: 14.44
+	Hs
		1060791 IMB1_HUMAN (11-871): 1.22e-86: 297: 17.83		BTNL9_HUMAN (14-289): 1.23e-48: 171: 14.44
+	Hs
		874565 XPO2_HUMAN (3-896): 5.07e-90: 308: 13.52		VSIG2_HUMAN (3-270): 3.76e-40: 144: 15.11
+	Hs
		312303 IPO7_HUMAN (11-850): 2.74e-78: 277: 13.25		BTNL9_HUMAN (14-289): 1.23e-48: 171: 14.44
+	Hs
		312358 IPO7_HUMAN (11-850): 2.74e-78: 277: 13.25		VSIG2_HUMAN (3-270): 3.76e-40: 144: 15.11
+	Hs
		127391 IPO5_HUMAN (20-627): 9.22e-15: 81.2: 10.75		PD1L1_HUMAN (1-290): 1.08e-62: 201: 100.00