Protein: FCHO2
F-BAR domain only protein 2

Gene: FCHO2
Organism: Homo sapiens
Interactions: 83
UniProt ID: Q0JRZ9

Gene Ontology (top 5):
GO:0001786 - phosphatidylserine binding
GO:0005546 - phosphatidylinositol-4,5-bisphosphate binding
GO:0005737 - cytoplasm
GO:0005829 - cytosol
GO:0005886 - plasma membrane

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

155659

FCHO1
F-BAR domain only protein 1

2

18

High-throughput

0.811

High

1022154

DAB2
Disabled homolog 2

4

8

Small-scale

0.705

High

839750

EPS15
Epidermal growth factor receptor substrate 15

4

20

Small-scale

0.699

High

1070511

AP2M1
AP-2 complex subunit mu

4

1

High-throughput

0.699

High

922569

AP2S1
AP-2 complex subunit sigma

4

4

High-throughput

0.697

High

1070490

FCHO2
F-BAR domain only protein 2

1

16

Small-scale

0.692

High

988954

AP2B1
AP-2 complex subunit beta

3

10

High-throughput

0.667

High

1070516

SPC25
Kinetochore protein Spc25

3

0

High-throughput

0.638

High

1070518

EP15R
Epidermal growth factor receptor substrate 15-like 1

2

19

Small-scale

0.619

High

483328

CLCB
Clathrin light chain B

2

1

High-throughput

0.611

High

507883

UBC
Polyubiquitin-C [Cleaved into: Ubiquitin]

2

5

High-throughput

0.602

High

1070505

RHOU
Rho-related GTP-binding protein RhoU

2

20

High-throughput

0.595

High

375456

RASK
GTPase KRas

2

15

High-throughput

0.584

High

540423

LAMP1
Lysosome-associated membrane glycoprotein 1

2

4

High-throughput

0.584

High

977960

RHOB
Rho-related GTP-binding protein RhoB

2

20

High-throughput

0.584

High

772764

MYH9
Myosin-9

1

2

High-throughput

0.536

High

866655

CAZA2
F-actin-capping protein subunit alpha-2

1

1

High-throughput

0.536

High

1070492

AP1B1
AP-1 complex subunit beta-1

1

10

High-throughput

0.536

High

1070494

PICAL
Phosphatidylinositol-binding clathrin assembly protein

1

3

High-throughput

0.536

High

1070500

DREB
Drebrin

1

5

High-throughput

0.536

High

1070512

MYO19
Unconventional myosin-XIX

1

3

High-throughput

0.536

High

1070519

LIMA1
LIM domain and actin-binding protein 1

1

4

High-throughput

0.536

High

1026001

CLH1
Clathrin heavy chain 1

1

0

High-throughput

0.513

High

1070503

MACC1
Metastasis-associated in colon cancer protein 1

1

0

High-throughput

0.513

High

1070517

GTSE1
G2 and S phase-expressed protein 1

1

0

High-throughput

0.513

High

1070497

ITSN1
Intersectin-1

1

14

Small-scale

0.501

High

126567

RHOD
Rho-related GTP-binding protein RhoD

1

20

High-throughput

0.479

High

172745

XPO1
Exportin-1

1

2

High-throughput

0.479

High

189532

STX7
Syntaxin-7

1

2

High-throughput

0.479

High

218110

TGON2
Trans-Golgi network integral membrane protein 2

1

5

High-throughput

0.479

High

341038

DIRA3
GTP-binding protein Di-Ras3

1

5

High-throughput

0.479

High

344677

AP2A1
AP-2 complex subunit alpha-1

1

10

Small-scale

0.479

High

363188

EGFR
Epidermal growth factor receptor

1

18

High-throughput

0.479

High

374550

RASH
GTPase HRas

1

11

High-throughput

0.479

High

463482

LYN
Tyrosine-protein kinase Lyn

1

10

High-throughput

0.479

High

465502

IGF1R
Insulin-like growth factor 1 receptor

1

20

High-throughput

0.479

High

483079

CLCA
Clathrin light chain A

1

1

High-throughput

0.479

High

541453

FGFR1
Fibroblast growth factor receptor 1

1

20

High-throughput

0.479

High

562027

LAMP2
Lysosome-associated membrane glycoprotein 2

1

4

High-throughput

0.479

High

581011

RAC2
Ras-related C3 botulinum toxin substrate 2

1

20

High-throughput

0.479

High

582766

EZRI
Ezrin

1

4

High-throughput

0.479

High

601256

RHOQ
Rho-related GTP-binding protein RhoQ

1

20

High-throughput

0.479

High

603950

CXA1
Gap junction alpha-1 protein

1

3

High-throughput

0.479

High

642829

KCNA3
Potassium voltage-gated channel subfamily A member 3

1

2

High-throughput

0.479

High

648495

FGFR4
Fibroblast growth factor receptor 4

1

20

High-throughput

0.479

High

659019

PTPRG
Receptor-type tyrosine-protein phosphatase gamma

1

6

High-throughput

0.479

High

710200

EPHA2
Ephrin type-A receptor 2

1

15

High-throughput

0.479

High

710819

EPHB2
Ephrin type-B receptor 2

1

11

High-throughput

0.479

High

830629

CCNF
Cyclin-F

1

2

High-throughput

0.479

High

931839

EPHA5
Ephrin type-A receptor 5

1

15

High-throughput

0.479

High

932059

EPHA4
Ephrin type-A receptor 4

1

11

High-throughput

0.479

High

953411

RAC3
Ras-related C3 botulinum toxin substrate 3

1

20

High-throughput

0.479

High

955098

CDC42
Cell division control protein 42 homolog

1

20

High-throughput

0.479

High

975005

ARF6
ADP-ribosylation factor 6

1

2

High-throughput

0.479

High

988316

RAC1
Ras-related C3 botulinum toxin substrate 1

1

20

High-throughput

0.479

High

1015391

RHOG
Rho-related GTP-binding protein RhoG

1

20

High-throughput

0.479

High

1070493

ANK3
Ankyrin-3

1

3

High-throughput

0.479

High

1070495

RAB35
Ras-related protein Rab-35

1

5

High-throughput

0.479

High

1070496

EPHA7
Ephrin type-A receptor 7

1

10

High-throughput

0.479

High

1070498

NTRK3
NT-3 growth factor receptor

1

20

High-throughput

0.479

High

1070499

OCLN
Occludin

1

2

High-throughput

0.479

High

1070501

LTOR1
Ragulator complex protein LAMTOR1

1

2

High-throughput

0.479

High

1070504

TRI67
Tripartite motif-containing protein 67

1

9

High-throughput

0.479

High

1070507

MIB1
E3 ubiquitin-protein ligase MIB1

1

3

High-throughput

0.479

High

1070509

BICD2
Protein bicaudal D homolog 2

1

6

High-throughput

0.479

High

1070514

RHOJ
Rho-related GTP-binding protein RhoJ

1

20

High-throughput

0.479

High

1070515

RHOF
Rho-related GTP-binding protein RhoF

1

20

High-throughput

0.479

High

1070520

UBQL2
Ubiquilin-2

1

1

High-throughput

0.479

High

1070521

MYO6
Unconventional myosin-VI

1

2

High-throughput

0.479

High

1070522

LAMP3
Lysosome-associated membrane glycoprotein 3

1

4

High-throughput

0.479

High

1070523

MB212
Protein mab-21-like 2

1

4

High-throughput

0.479

High

184287

NPHP1
Nephrocystin-1

1

0

High-throughput

0.458

High

459564

PROF1
Profilin-1

1

0

High-throughput

0.458

High

986372

PPIA
Peptidyl-prolyl cis-trans isomerase A

1

0

High-throughput

0.458

High

1070513

PACN1
Protein kinase C and casein kinase substrate in neurons protein 1

1

18

High-throughput

0.457

High

1070502

PKHA7
Pleckstrin homology domain-containing family A member 7

1

9

High-throughput

0.445

High

1070524

SNX9
Sorting nexin-9

1

3

High-throughput

0.445

High

327239

ZFPL1
Zinc finger protein-like 1

1

1

High-throughput

0.437

High

1070491

CGNL1
Cingulin-like protein 1

1

3

High-throughput

0.437

High

1070510

CK052
Uncharacterized protein C11orf52

1

2

High-throughput

0.437

High

1070508

S2541
Mitochondrial carrier protein SCaMC-3L

3

0

High-throughput

0.347

High

1070506

ATG9A
Autophagy-related protein 9A

1

0

High-throughput

0.249

Low


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Last updated: 11Aug2025