HitPredict

Interactor 1: FFAR1 (O14842)
Free fatty acid receptor 1 (G-protein coupled receptor 40)
Gene: FFAR1

Interactor 2: MIRO1 (Q8IXI2)
Mitochondrial Rho GTPase 1 (MIRO-1) (hMiro-1) (EC 3.6.5.-) (Rac-GTP-binding protein-like protein) (Ras homolog gene family member T1)
Gene: RHOT1

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.47	0.50	0.489

Property	Details
Experiments	33961781
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	-
Homologous interactions	18

Homologous interactions

Color coding for hit scores

	1 300 Hs			1 618
+	Hs
		723343 APJ_HUMAN (4-299): 4.6e-67: 215: 19.68		MIRO2_HUMAN (1-618): 0: 764: 59.81
+	Hs
		156868 FFAR1_HUMAN (1-300): 1.82e-64: 206: 100.00		MIRO2_HUMAN (1-618): 0: 764: 59.81
+	Hs
		876153 PAR2_HUMAN (2-280): 2.1e-54: 183: 20.91		MIRO2_HUMAN (1-618): 0: 764: 59.81
+	Hs
		1067534 P2RY6_HUMAN (7-281): 2.06e-49: 168: 24.49		MIRO2_HUMAN (1-618): 0: 764: 59.81
+	Hs
		723282 APJ_HUMAN (4-299): 4.6e-67: 215: 19.68		RAB13_HUMAN (5-191): 1e-71: 231: 19.59
+	Hs
		895604 CXCR4_HUMAN (3-280): 4.27e-65: 209: 20.69		RAC1_HUMAN (3-181): 7.62e-73: 234: 23.83
+	Hs
		686638 CCR1_HUMAN (3-280): 8.74e-69: 219: 21.53		RHOG_HUMAN (3-170): 8.87e-68: 220: 25.28
+	Hs
		156807 FFAR1_HUMAN (1-300): 1.82e-64: 206: 100.00		RAB13_HUMAN (5-191): 1e-71: 231: 19.59
+	Hs
		545298 CXCR4_HUMAN (3-280): 4.27e-65: 209: 20.69		RAC2_HUMAN (3-185): 6.9e-70: 226: 23.86
+	Hs
		892299 CXCR4_HUMAN (3-280): 4.27e-65: 209: 20.69		RAC3_HUMAN (3-168): 4.28e-70: 226: 23.89
+	Hs
		686631 CCR1_HUMAN (3-280): 8.74e-69: 219: 21.53		RHOA_HUMAN (6-186): 1.33e-65: 214: 23.59
+	Hs
		895605 CXCR4_HUMAN (3-280): 4.27e-65: 209: 20.69		RHOG_HUMAN (3-170): 8.87e-68: 220: 25.28
+	Hs
		674840 AGTR1_HUMAN (2-292): 1.09e-58: 193: 19.74		RB11A_HUMAN (5-201): 1.75e-71: 231: 19.60
+	Hs
		895599 CXCR4_HUMAN (3-280): 4.27e-65: 209: 20.69		RHOA_HUMAN (6-186): 1.33e-65: 214: 23.59
+	Hs
		783818 CCR2_HUMAN (2-284): 2.43e-58: 193: 19.80		RHOG_HUMAN (3-170): 8.87e-68: 220: 25.28
+	Hs
		120278 ADRB2_HUMAN (10-292): 1.55e-67: 217: 15.67		RHOD_HUMAN (3-171): 2.64e-11: 65.5: 27.87
+	Hs
		895738 CXCR4_HUMAN (3-280): 4.27e-65: 209: 20.69		RHOF_HUMAN (2-167): 3.85e-11: 64.7: 28.33
+	Hs
		895602 CXCR4_HUMAN (3-280): 4.27e-65: 209: 20.69		RHOB_HUMAN (6-168): 6.46e-10: 60.8: 25.99