HitPredict

Interactor 1: LIN7A (O14910)
Protein lin-7 homolog A (Lin-7A) (hLin-7) (Mammalian lin-seven protein 1) (MALS-1) (Tax interaction protein 33) (TIP-33) (Vertebrate lin-7 homolog 1) (Veli-1)
Gene: LIN7A

Interactor 2: NMDE2 (Q13224)
Glutamate receptor ionotropic, NMDA 2B (GluN2B) (Glutamate [NMDA] receptor subunit epsilon-2) (N-methyl D-aspartate receptor subtype 2B) (NMDAR2B) (NR2B) (N-methyl-D-aspartate receptor subunit 3) (NR3) (hNR3)
Gene: GRIN2B

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.41	0.60	0.501

Property	Details
Experiments	10341223
Identification Methods	pull down
Interaction Type	direct interaction

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005886 - plasma membrane GO:0098839 - postsynaptic density membrane
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 233 Hs			1 1484
+	Hs
		1028152 LIN7B_HUMAN (18-214): 2.73e-51: 167: 78.17		NMDE2_HUMAN (1-1484): 0: 1846: 100.00
+	Rn
		962670 LIN7B_RAT (18-214): 2.15e-51: 167: 78.17		NMDE2_RAT (1-1484): 0: 1829: 98.45
+	Mm
		292486 LIN7C_MOUSE (18-211): 1.25e-50: 165: 79.38		NMDE2_MOUSE (1-1484): 0: 1826: 98.45
+	Hs
		1028140 DLG2_HUMAN (5-212): 1.01e-26: 109: 20.09		NMDE2_HUMAN (1-1484): 0: 1846: 100.00
+	Hs
		1021485 DLG1_HUMAN (29-232): 8.11e-25: 104: 19.63		NMDE2_HUMAN (1-1484): 0: 1846: 100.00
+	Rn
		962666 DLG2_RAT (5-212): 6.61e-27: 110: 20.56		NMDE2_RAT (1-1484): 0: 1829: 98.45
+	Mm
		963769 DLG2_MOUSE (5-212): 6.61e-27: 110: 20.56		NMDE2_MOUSE (1-1484): 0: 1826: 98.45
+	Rn
		962657 DLG2_RAT (5-212): 6.61e-27: 110: 20.56		NMDE1_RAT (9-1484): 0: 1506: 52.59
+	Hs
		1018896 DLG2_HUMAN (5-212): 1.01e-26: 109: 20.09		NMDE1_HUMAN (9-1484): 0: 1495: 52.39
+	Hs
		1018888 DLG1_HUMAN (29-232): 8.11e-25: 104: 19.63		NMDE1_HUMAN (9-1484): 0: 1495: 52.39
+	Hs
		1021492 DLG1_HUMAN (29-232): 8.11e-25: 104: 19.63		NMDE3_HUMAN (10-929): 0: 770: 54.01
+	Hs
		1021483 DLG1_HUMAN (29-232): 8.11e-25: 104: 19.63		GRIK2_HUMAN (9-902): 0: 733: 19.96
+	Mm
		620904 DLG2_MOUSE (5-212): 6.61e-27: 110: 20.56		GRIA1_MOUSE (11-901): 0: 691: 19.48
+	Mm
		620892 DLG4_MOUSE (5-232): 6.08e-25: 104: 18.33		GRIA1_MOUSE (11-901): 0: 691: 19.48
+	Hs
		786696 DLG1_HUMAN (29-232): 8.11e-25: 104: 19.63		GRIA1_HUMAN (16-901): 0: 690: 19.56
+	Hs
		178307 DLG1_HUMAN (29-232): 8.11e-25: 104: 19.63		NMDE4_HUMAN (35-871): 0: 689: 54.03
+	Mm
		723606 DLG2_MOUSE (5-212): 6.61e-27: 110: 20.56		NMDZ1_MOUSE (14-940): 0: 671: 23.52
+	Hs
		984257 DLG1_HUMAN (29-232): 8.11e-25: 104: 19.63		NMDZ1_HUMAN (13-940): 0: 668: 23.60
+	Mm
		620965 DLG4_MOUSE (5-232): 6.08e-25: 104: 18.33		GRIA2_MOUSE (16-871): 0: 665: 20.94
+	Mm
		57144 DLG4_MOUSE (5-232): 6.08e-25: 104: 18.33		A2AI21_MOUSE (14-940): 0: 664: 22.96