HitPredict

Interactor 1: CSKP (O14936)
Peripheral plasma membrane protein CASK (hCASK) (EC 2.7.11.1) (Calcium/calmodulin-dependent serine protein kinase) (Protein lin-2 homolog)
Gene: CASK

Interactor 2: KINH (P33176)
Kinesin-1 heavy chain (Conventional kinesin heavy chain) (Ubiquitous kinesin heavy chain) (UKHC)
Gene: KIF5B

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.47	0.60	0.536

Property	Details
Experiments	32707033
Identification Methods	affinity chromatography technology, pull down
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005524 - ATP binding GO:0005829 - cytosol GO:0031982 - vesicle
Homologous interactions	17

Homologous interactions

Color coding for hit scores

	1 926 Hs			1 963
+	Hs
		159121 CSKP_HUMAN (1-926): 0: 973: 100.00		KIF1B_HUMAN (4-836): 4.2e-112: 382: 23.49
+	Ce
		619838 LIN2_CAEEL (2-926): 0: 744: 45.21		UN104_CAEEL (7-630): 1.09e-107: 368: 25.99
+	Hs
		855629 DLG1_HUMAN (405-923): 2.05e-144: 453: 21.91		KIF11_HUMAN (8-877): 3.01e-160: 500: 26.43
+	Mm
		1160656 DLG1_MOUSE (405-923): 1.81e-145: 456: 22.06		KIF11_MOUSE (8-922): 2.48e-150: 474: 24.28
+	Hs
		702930 MARK2_HUMAN (4-680): 5.16e-140: 438: 18.64		KINH_HUMAN (1-963): 5.26e-144: 455: 100.00
+	Hs
		1021567 DLG1_HUMAN (405-923): 2.05e-144: 453: 21.91		KI13B_HUMAN (4-760): 3.86e-116: 394: 23.32
+	Hs
		942384 DLG4_HUMAN (402-922): 1.14e-145: 451: 22.56		KI13B_HUMAN (4-760): 3.86e-116: 394: 23.32
+	Mm
		93501 DLG4_MOUSE (402-922): 5.68e-145: 449: 22.37		E9Q4K7_MOUSE (4-760): 5.98e-114: 387: 24.03
+	Hs
		231509 DLG1_HUMAN (405-923): 2.05e-144: 453: 21.91		KIF1B_HUMAN (4-836): 4.2e-112: 382: 23.49
+	Hs
		231496 DLG4_HUMAN (402-922): 1.14e-145: 451: 22.56		KIF1B_HUMAN (4-836): 4.2e-112: 382: 23.49
+	Rn
		292061 DLG1_RAT (434-923): 3.1e-143: 450: 22.61		KIF1B_RAT (4-759): 1.47e-112: 383: 24.59
+	Hs
		1183134 MARK2_HUMAN (4-680): 5.16e-140: 438: 18.64		KI13B_HUMAN (4-760): 3.86e-116: 394: 23.32
+	Rn
		292059 DLG4_RAT (402-922): 3.56e-145: 449: 22.56		KIF1B_RAT (4-759): 1.47e-112: 383: 24.59
+	Hs
		231550 MPP7_HUMAN (354-926): 1.78e-145: 445: 30.81		KIF1B_HUMAN (4-836): 4.2e-112: 382: 23.49
+	Mm
		660025 DLG4_MOUSE (402-922): 5.68e-145: 449: 22.37		KIF3A_MOUSE (689-928): 1.02e-12: 74: 14.46
+	Mm
		702841 DLG4_MOUSE (402-922): 5.68e-145: 449: 22.37		KIF5A_MOUSE (575-960): 4.34e-11: 69.1: 8.11
+	Rn
		506762 KCC2A_RAT (8-312): 5.96e-85: 282: 46.08		KIF5A_RAT (593-962): 3.76e-13: 76: 11.26