Interactor 1: DSCAM (O60469)
Cell adhesion molecule DSCAM (CHD2) (Down syndrome cell adhesion molecule)
Gene: DSCAM

Interactor 2: SEM4D (Q92854)
Semaphorin-4D (A8) (BB18) (GR3) (CD antigen CD100)
Gene: SEMA4D

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score Annotation score Interaction score
0.48 1.00 0.698

The method score is based on:

Property Details
Experiments 35914814
Identification Methods two hybrid, two hybrid fragment pooling approach
Interaction Type direct interaction, physical association

The annotation score is based on:

Property Details
Interacting Pfam domains fn3~ig, ig~I-set, Ig_3~ig
Common GO terms GO:0005886 - plasma membrane
GO:0007155 - cell adhesion
GO:0007162 - negative regulation of cell adhesion
GO:0007411 - axon guidance
Homologous interactions 3

Homologous interactions

Color coding for hit scores

1 2012
Hs

1 862
+ Hs
+ Dm
+ Dm

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024