HitPredict

Interactor 1: CSKP (O14936)
Peripheral plasma membrane protein CASK (hCASK) (EC 2.7.11.1) (Calcium/calmodulin-dependent serine protein kinase) (Protein lin-2 homolog)
Gene: CASK

Interactor 2: RHOG (P84095)
Rho-related GTP-binding protein RhoG
Gene: RHOG

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	1.00	0.618

Property	Details
Experiments	31871319
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	PDZ~Ras, Pkinase~Ras
Common GO terms	GO:0005829 - cytosol GO:0005886 - plasma membrane GO:0005925 - focal adhesion
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 926 Hs			1 191
+	Hs
		159189 CSKP_HUMAN (1-926): 0: 973: 100.00		RAC1_HUMAN (1-191): 3.6e-82: 243: 71.88
+	Hs
		159149 CSKP_HUMAN (1-926): 0: 973: 100.00		RAC2_HUMAN (1-191): 1.28e-78: 234: 71.35
+	Hs
		159184 CSKP_HUMAN (1-926): 0: 973: 100.00		CDC42_HUMAN (1-191): 1.3e-78: 234: 60.73
+	Hs
		159153 CSKP_HUMAN (1-926): 0: 973: 100.00		RHOQ_HUMAN (4-189): 5.74e-73: 220: 56.84
+	Hs
		925239 DLG1_HUMAN (405-923): 2.05e-144: 453: 21.91		RAC1_HUMAN (1-191): 3.6e-82: 243: 71.88
+	Hs
		950954 DLG1_HUMAN (405-923): 2.05e-144: 453: 21.91		RHOG_HUMAN (1-191): 9.12e-82: 242: 100.00
+	Mm
		925797 DLG4_MOUSE (402-922): 5.68e-145: 449: 22.37		RAC1_MOUSE (1-191): 3.6e-82: 243: 71.88
+	Hs
		894207 PALS1_HUMAN (361-925): 9.64e-148: 454: 27.84		CDC42_HUMAN (1-191): 1.3e-78: 234: 60.73
+	Hs
		900683 PALS1_HUMAN (361-925): 9.64e-148: 454: 27.84		RHOA_HUMAN (5-191): 1.26e-78: 234: 55.62
+	Hs
		545346 DLG1_HUMAN (405-923): 2.05e-144: 453: 21.91		RAC2_HUMAN (1-191): 1.28e-78: 234: 71.35
+	Hs
		893948 DLG1_HUMAN (405-923): 2.05e-144: 453: 21.91		CDC42_HUMAN (1-191): 1.3e-78: 234: 60.73
+	Hs
		900424 DLG1_HUMAN (405-923): 2.05e-144: 453: 21.91		RHOA_HUMAN (5-191): 1.26e-78: 234: 55.62
+	Hs
		436278 DLG1_HUMAN (405-923): 2.05e-144: 453: 21.91		RHOC_HUMAN (5-191): 8.34e-77: 230: 56.15
+	Mm
		1111996 DLG4_MOUSE (402-922): 5.68e-145: 449: 22.37		Q3TLP8_MOUSE (1-191): 1.22e-77: 232: 64.93
+	Hs
		545425 MPP7_HUMAN (354-926): 1.78e-145: 445: 30.81		RAC2_HUMAN (1-191): 1.28e-78: 234: 71.35
+	Hs
		892341 DLG1_HUMAN (405-923): 2.05e-144: 453: 21.91		RAC3_HUMAN (1-177): 1.67e-75: 226: 72.88
+	Hs
		436349 MPP7_HUMAN (354-926): 1.78e-145: 445: 30.81		RHOC_HUMAN (5-191): 8.34e-77: 230: 56.15
+	Hs
		564500 DLG1_HUMAN (405-923): 2.05e-144: 453: 21.91		RHOQ_HUMAN (4-189): 5.74e-73: 220: 56.84
+	Hs
		892418 MPP7_HUMAN (354-926): 1.78e-145: 445: 30.81		RAC3_HUMAN (1-177): 1.67e-75: 226: 72.88
+	Hs
		564561 MPP7_HUMAN (354-926): 1.78e-145: 445: 30.81		RHOQ_HUMAN (4-189): 5.74e-73: 220: 56.84