Protein: DEMA
Dematin (Dematin actin-binding protein) (Erythrocyte membrane protein band 4.9)

Gene: DEMA, DMTN
Organism: Homo sapiens
Interactions: 34
UniProt ID: Q08495

Gene Ontology (top 5):
GO:0003779 - actin binding
GO:0005102 - signaling receptor binding
GO:0005790 - smooth endoplasmic reticulum
GO:0005829 - cytosol
GO:0005884 - actin filament

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

729777

1433B
14-3-3 protein beta/alpha

5

20

High-throughput

0.716

High

971442

1433E
14-3-3 protein epsilon

4

5

High-throughput

0.694

High

990143

1433Z
14-3-3 protein zeta/delta

4

20

High-throughput

0.694

High

966240

1433G
14-3-3 protein gamma

3

20

High-throughput

0.678

High

1049230

1433F
14-3-3 protein eta

3

20

High-throughput

0.667

High

690942

1433T
14-3-3 protein theta

3

20

High-throughput

0.650

High

1064351

DPP9
Dipeptidyl peptidase 9

3

0

High-throughput

0.638

High

1064353

UBR1
E3 ubiquitin-protein ligase UBR1

3

0

High-throughput

0.638

High

952777

ACTB
Actin, cytoplasmic 1

1

20

High-throughput

0.618

High

730541

1433S
14-3-3 protein sigma

2

20

High-throughput

0.611

High

1064347

TRAF2
TNF receptor-associated factor 2

2

3

High-throughput

0.606

High

1064355

CEP76
Centrosomal protein of 76 kDa

2

0

High-throughput

0.580

High

1064354

TEX11
Testis-expressed protein 11

2

1

High-throughput

0.553

High

529698

TAU
Microtubule-associated protein tau

1

5

High-throughput

0.536

High

1064356

MIB2
E3 ubiquitin-protein ligase MIB2

1

7

High-throughput

0.536

High

1063213

GOGA2
Golgin subfamily A member 2

1

13

High-throughput

0.523

High

210558

DC1L2
Cytoplasmic dynein 1 light intermediate chain 2

1

0

High-throughput

0.518

High

1064352

PTOV1
Prostate tumor-overexpressed gene 1 protein

1

0

High-throughput

0.518

High

1064360

EPCR
Endothelial protein C receptor

1

0

High-throughput

0.518

High

421991

A4
Amyloid-beta precursor protein

1

2

High-throughput

0.501

High

791336

SYUA
Alpha-synuclein

1

1

Small-scale

0.501

High

1064357

NED4L
E3 ubiquitin-protein ligase NEDD4-like

1

1

High-throughput

0.501

High

371865

MYC
Myc proto-oncogene protein

1

5

High-throughput

0.479

High

1064349

A16L1
Autophagy-related protein 16-1

1

7

High-throughput

0.479

High

1064358

KPCD2
Serine/threonine-protein kinase D2

1

3

High-throughput

0.479

High

1064359

ANLN
Anillin

1

3

High-throughput

0.479

High

874031

TPC10
Trafficking protein particle complex subunit 10

1

0

High-throughput

0.458

High

982927

RS25
Small ribosomal subunit protein eS25

1

0

High-throughput

0.458

High

1064348

NU188
Nucleoporin NUP188

1

0

High-throughput

0.458

High

974529

SMD2
Small nuclear ribonucleoprotein Sm D2

1

1

High-throughput

0.457

High

105822

APRIO
Alternative prion protein

1

5

High-throughput

0.437

High

1064350

CR3L2
Cyclic AMP-responsive element-binding protein 3-like protein 2

1

4

High-throughput

0.407

High

332299

ATE1
Arginyl-tRNA--protein transferase 1

1

0

High-throughput

0.279

Low

578604

CBPA3
Mast cell carboxypeptidase A

1

0

High-throughput

0.269

Low


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Last updated: 11Aug2025