Protein: MAGI3
Membrane-associated guanylate kinase, WW and PDZ domain-containing protein 3 (Membrane-associated guanylate kinase inverted 3) (MAGI-3)

Gene: MAGI3
Organism: Homo sapiens
Interactions: 57
UniProt ID: Q5TCQ9

Gene Ontology (top 5):
GO:0004385 - GMP kinase activity
GO:0005109 - frizzled binding
GO:0005524 - ATP binding
GO:0005634 - nucleus
GO:0005737 - cytoplasm

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

658826

PTPRB
Receptor-type tyrosine-protein phosphatase beta

1

20

Small-scale

0.740

High

249149

DSCAM
Cell adhesion molecule DSCAM

1

20

High-throughput

0.698

High

180995

LRAD4
Low-density lipoprotein receptor class A domain-containing protein 4

3

3

High-throughput

0.667

High

292492

RHBL1
Rhomboid-related protein 1

3

3

High-throughput

0.667

High

352629

TCL1B
T-cell leukemia/lymphoma protein 1B

3

2

High-throughput

0.667

High

1215973

DSCL1
Cell adhesion molecule DSCAML1

1

20

Small-scale

0.656

High

1215975

NRCAM
Neuronal cell adhesion molecule

1

20

Small-scale

0.656

High

1151991

PTN14
Tyrosine-protein phosphatase non-receptor type 14

2

20

High-throughput

0.628

High

1215976

FERM1
Fermitin family homolog 1

2

1

High-throughput

0.628

High

1215974

PARD3
Partitioning defective 3 homolog

1

20

High-throughput

0.618

High

1215984

RPGF2
Rap guanine nucleotide exchange factor 2

1

9

High-throughput

0.618

High

1215968

CAVN1
Caveolae-associated protein 1

2

0

High-throughput

0.602

High

155244

AGRB1
Adhesion G protein-coupled receptor B1

2

15

Small-scale

0.595

High

472225

ADRB1
Beta-1 adrenergic receptor

1

20

Small-scale

0.589

High

1215982

PIN4
Peptidyl-prolyl cis-trans isomerase NIMA-interacting 4

1

0

High-throughput

0.586

High

951710

PTEN
Phosphatidylinositol 3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN

1

7

Small-scale

0.586

High

1215970

ARHG8
Neuroepithelial cell-transforming gene 1 protein

2

20

High-throughput

0.571

High

372256

MYC
Myc proto-oncogene protein

1

4

Small-scale

0.561

High

458428

ADRB2
Beta-2 adrenergic receptor

1

20

Small-scale

0.561

High

764822

CTNB1
Catenin beta-1

1

20

Small-scale

0.561

High

1215977

TMG4
Transmembrane gamma-carboxyglutamic acid protein 4

1

4

Small-scale

0.561

High

1056784

FMR1
Fragile X messenger ribonucleoprotein 1

1

18

High-throughput

0.541

High

992208

SKP1
S-phase kinase-associated protein 1

1

0

Small-scale

0.537

High

157485

CTRO
Citron Rho-interacting kinase

1

20

High-throughput

0.536

High

744462

SSR3
Somatostatin receptor type 3

1

20

Small-scale

0.536

High

1215983

DLGP4
Disks large-associated protein 4

1

20

High-throughput

0.536

High

1029859

RUNX1
Runt-related transcription factor 1

1

0

High-throughput

0.518

High

1215978

MED28
Mediator of RNA polymerase II transcription subunit 28

1

1

Small-scale

0.515

High

1215981

PLXB3
Plexin-B3

1

11

Small-scale

0.508

High

376613

TGFA
Protransforming growth factor alpha [Cleaved into: Transforming growth factor alpha

1

2

Small-scale

0.501

High

762204

CRFR1
Corticotropin-releasing factor receptor 1

1

20

Small-scale

0.501

High

1060788

ACK1
Activated CDC42 kinase 1

1

20

Small-scale

0.501

High

1098524

NMDE2
Glutamate receptor ionotropic, NMDA 2B

1

20

Small-scale

0.494

High

1215969

UBP43
Ubiquitin carboxyl-terminal hydrolase 43

1

3

High-throughput

0.489

High

1040830

MECOM
Histone-lysine N-methyltransferase MECOM

1

7

High-throughput

0.481

High

468477

HS90B
Heat shock protein HSP 90-beta

1

5

High-throughput

0.479

High

535164

BIP
Endoplasmic reticulum chaperone BiP

1

11

High-throughput

0.479

High

556142

CADH1
Cadherin-1

1

10

High-throughput

0.479

High

642920

KCNA3
Potassium voltage-gated channel subfamily A member 3

1

20

High-throughput

0.479

High

731382

STIP1
Stress-induced-phosphoprotein 1

1

5

High-throughput

0.479

High

828804

MDHM
Malate dehydrogenase, mitochondrial

1

2

High-throughput

0.479

High

966439

1433G
14-3-3 protein gamma

1

20

High-throughput

0.479

High

1024069

TFAM
Transcription factor A, mitochondrial

1

4

High-throughput

0.479

High

1049389

1433F
14-3-3 protein eta

1

20

High-throughput

0.479

High

1112541

CUL1
Cullin-1

1

9

Small-scale

0.479

High

1113335

CUL3
Cullin-3

1

9

High-throughput

0.479

High

1215967

RN123
E3 ubiquitin-protein ligase RNF123

1

3

High-throughput

0.479

High

1215972

BICD2
Protein bicaudal D homolog 2

1

16

High-throughput

0.479

High

1215980

XPO7
Exportin-7

1

5

High-throughput

0.479

High

255063

HCN1
Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 1

1

5

High-throughput

0.445

High

1199501

KLH22
Kelch-like protein 22

1

10

High-throughput

0.445

High

1215971

RYBP
RING1 and YY1-binding protein

1

1

High-throughput

0.445

High

1215979

RN146
E3 ubiquitin-protein ligase RNF146

1

5

Small-scale

0.445

High

1099109

SRSF5
Serine/arginine-rich splicing factor 5

1

4

High-throughput

0.437

High

349122

LATS1
Serine/threonine-protein kinase LATS1

1

20

Small-scale

0.408

High

1148345

KS6A1
Ribosomal protein S6 kinase alpha-1

1

17

Small-scale

0.408

High

335619

AGM1
Phosphoacetylglucosamine mutase

1

0

High-throughput

0.249

Low


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Last updated: 11Aug2025