HitPredict

Interactor 1: HGS (O14964)
Hepatocyte growth factor-regulated tyrosine kinase substrate (Hrs) (Protein pp110)
Gene: HGS

Interactor 2: PGFRA (P16234)
Platelet-derived growth factor receptor alpha (PDGF-R-alpha) (PDGFR-alpha) (EC 2.7.10.1) (Alpha platelet-derived growth factor receptor) (Alpha-type platelet-derived growth factor receptor) (CD140 antigen-like family member A) (CD140a antigen) (Platelet-derived growth factor alpha receptor) (Platelet-derived growth factor receptor 2) (PDGFR-2) (CD antigen CD140a)
Gene: PDGFRA

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.50	0.437

Property	Details
Experiments	35384245
Identification Methods	proximity labelling technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	-
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 777 Hs			1 1089
+	Hs
		276999 STAM2_HUMAN (4-521): 4.17e-52: 191: 15.91		PGFRA_HUMAN (1-1089): 0: 817: 100.00
+	Hs
		159856 HGS_HUMAN (1-777): 5.12e-104: 338: 100.00		PGFRB_HUMAN (29-1089): 0: 650: 43.33
+	Hs
		276989 STAM2_HUMAN (4-521): 4.17e-52: 191: 15.91		PGFRB_HUMAN (29-1089): 0: 650: 43.33
+	Hs
		159889 HGS_HUMAN (1-777): 5.12e-104: 338: 100.00		FGFR3_HUMAN (745-969): 1.84e-76: 270: 40.74
+	Hs
		160015 HGS_HUMAN (1-777): 5.12e-104: 338: 100.00		NTRK2_HUMAN (48-776): 2.93e-51: 197: 14.04
+	Rn
		1144355 HGS_RAT (1-777): 3.19e-100: 328: 93.44		NTRK2_RAT (87-776): 3.54e-53: 202: 14.10
+	Hs
		159885 HGS_HUMAN (1-777): 5.12e-104: 338: 100.00		FGFR2_HUMAN (6-339): 9.02e-49: 189: 14.90
+	Mm
		546322 HGS_MOUSE (1-777): 2.55e-98: 323: 93.31		NTRK2_MOUSE (53-776): 3.36e-53: 202: 13.62
+	Hs
		277004 STAM2_HUMAN (4-521): 4.17e-52: 191: 15.91		FGFR3_HUMAN (745-969): 1.84e-76: 270: 40.74
+	Hs
		159848 HGS_HUMAN (1-777): 5.12e-104: 338: 100.00		RET_HUMAN (573-690): 7.85e-22: 104: 43.22
+	Hs
		159888 HGS_HUMAN (1-777): 5.12e-104: 338: 100.00		FGFR4_HUMAN (3-221): 4.21e-22: 104: 8.36
+	Hs
		159845 HGS_HUMAN (1-777): 5.12e-104: 338: 100.00		CSF1R_HUMAN (212-602): 7.71e-15: 81.4: 10.59
+	Hs
		159864 HGS_HUMAN (1-777): 5.12e-104: 338: 100.00		FGFR1_HUMAN (3-177): 1.39e-14: 80.7: 10.71
+	Hs
		160014 HGS_HUMAN (1-777): 5.12e-104: 338: 100.00		NTRK3_HUMAN (28-227): 3.23e-13: 76.1: 9.01
+	Hs
		277074 STAM2_HUMAN (4-521): 4.17e-52: 191: 15.91		NTRK2_HUMAN (48-776): 2.93e-51: 197: 14.04
+	Hs
		277002 STAM2_HUMAN (4-521): 4.17e-52: 191: 15.91		FGFR2_HUMAN (6-339): 9.02e-49: 189: 14.90
+	Hs
		276988 STAM2_HUMAN (4-521): 4.17e-52: 191: 15.91		RET_HUMAN (573-690): 7.85e-22: 104: 43.22
+	Hs
		277003 STAM2_HUMAN (4-521): 4.17e-52: 191: 15.91		FGFR4_HUMAN (3-221): 4.21e-22: 104: 8.36
+	Hs
		276996 STAM2_HUMAN (4-521): 4.17e-52: 191: 15.91		FGFR1_HUMAN (3-177): 1.39e-14: 80.7: 10.71
+	Hs
		277073 STAM2_HUMAN (4-521): 4.17e-52: 191: 15.91		NTRK3_HUMAN (28-227): 3.23e-13: 76.1: 9.01