Protein: DSH
Segment polarity protein dishevelled

Gene: DSH
Organism: Drosophila melanogaster
Interactions: 116
UniProt ID: P51140

Gene Ontology (top 5):
GO:0000132 - establishment of mitotic spindle orientation
GO:0001736 - establishment of planar polarity
GO:0001737 - establishment of imaginal disc-derived wing hair orientation
GO:0001745 - compound eye morphogenesis
GO:0001751 - compound eye photoreceptor cell differentiation

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

900647

Q95TT5
LD24616p

2

19

Small-scale

0.808

High

900655

AXN
Axin

3

15

Small-scale

0.806

High

900637

Q8IPP3
Canoe, isoform D

2

19

Small-scale

0.800

High

900681

FRIZ2
Frizzled-2

2

20

Small-scale

0.775

High

723778

DLG1
Disks large 1 tumor suppressor protein

2

18

Small-scale

0.754

High

451740

NOTCH
Neurogenic locus Notch protein [Cleaved into: Processed neurogenic locus Notch protein]

7

6

Small-scale

0.746

High

900646

EBI
F-box-like/WD repeat-containing protein ebi

2

6

High-throughput

0.737

High

900680

NKD
Protein naked cuticle

5

10

Small-scale

0.732

High

615257

FRIZ
Frizzled

2

20

Small-scale

0.723

High

52390

PRIC1
Protein prickle

3

12

Small-scale

0.650

High

53367

A1Z7N9
Vang-like protein

3

20

Small-scale

0.640

High

900613

UBX
Homeotic protein ultrabithorax

2

5

Small-scale

0.637

High

57045

A1ZAN6
Rho guanine nucleotide exchange factor 2, isoform D

1

20

Small-scale

0.618

High

900618

Q0KHR3
Bazooka, isoform B

1

18

Small-scale

0.618

High

900654

FRIZ4
Frizzled-4

1

20

Small-scale

0.618

High

362466

ABL
Tyrosine-protein kinase Abl

1

20

Small-scale

0.604

High

900626

Q7JUF2
Diego, isoform A

1

17

Small-scale

0.586

High

118813

M9NFI9
Neurabin-1

1

20

High-throughput

0.575

High

674010

BRM
ATP-dependent helicase brm

2

1

High-throughput

0.571

High

900636

OSA
Trithorax group protein osa

2

2

High-throughput

0.571

High

900649

Q960F7
SD03629p

2

8

High-throughput

0.571

High

900659

Q9VEB9
Sequence-specific single-stranded DNA-binding protein, isoform A

2

3

High-throughput

0.571

High

900669

MED4
Mediator of RNA polymerase II transcription subunit 4

2

1

High-throughput

0.571

High

900671

CPSF6
Cleavage and polyadenylation specificity factor subunit 6

2

3

High-throughput

0.571

High

900672

CDK8
Cyclin-dependent kinase 8

2

3

High-throughput

0.571

High

900687

Q9W0L7
ubiquitinyl hydrolase 1

2

1

High-throughput

0.571

High

900695

MED15
Mediator of RNA polymerase II transcription subunit 15

2

3

High-throughput

0.571

High

900693

Q9W3N8
non-specific serine/threonine protein kinase

1

14

Small-scale

0.561

High

195850

FUZZY
Protein fuzzy

1

1

Small-scale

0.552

High

900614

MED20
Mediator of RNA polymerase II transcription subunit 20

2

0

High-throughput

0.547

High

900619

Q24090
GH08712p

2

0

High-throughput

0.547

High

900630

MED13
Mediator of RNA polymerase II transcription subunit 13

2

0

High-throughput

0.547

High

900640

ENC
Protein encore

2

0

High-throughput

0.547

High

900641

MED6
Mediator of RNA polymerase II transcription subunit 6

2

0

High-throughput

0.547

High

900645

MESD
LDLR chaperone boca

2

0

High-throughput

0.547

High

900653

LAR4
La-related protein Larp4B

2

0

High-throughput

0.547

High

900660

MED17
Mediator of RNA polymerase II transcription subunit 17

2

0

High-throughput

0.547

High

900661

Q9VF03
Brahma associated protein 155 kDa

2

0

High-throughput

0.547

High

900662

Q9VL29
GEO11246p1

2

0

High-throughput

0.547

High

900665

MED27
Mediator of RNA polymerase II transcription subunit 27

2

0

High-throughput

0.547

High

900679

MED11
Mediator of RNA polymerase II transcription subunit 11

2

0

High-throughput

0.547

High

900684

BAP60
Brahma-associated protein of 60 kDa

2

0

High-throughput

0.547

High

900688

MED30
Mediator of RNA polymerase II transcription subunit 30

2

0

High-throughput

0.547

High

900694

MED18
Mediator of RNA polymerase II transcription subunit 18

2

0

High-throughput

0.547

High

197570

PAX6
Paired box protein Pax-6

1

2

High-throughput

0.541

High

900616

Q0E8K8
FI21816p1

1

8

High-throughput

0.536

High

900632

Q7YZA4
Dishevelled associated activator of morphogenesis, isoform A

1

5

Small-scale

0.536

High

900624

Q6NLM8
RE56731p

1

0

Small-scale

0.529

High

900666

FRITZ
WD repeat-containing and planar cell polarity effector protein fritz

1

0

Small-scale

0.529

High

53560

A1Z813
Secretory 24AB, isoform A

2

3

High-throughput

0.521

High

900658

MED25
Mediator of RNA polymerase II transcription subunit 25

2

4

High-throughput

0.521

High

900673

Q9VUB7
PAX-interacting protein 1

2

12

High-throughput

0.521

High

900690

MED23
Mediator of RNA polymerase II transcription subunit 23

2

1

High-throughput

0.521

High

356738

CHDM
Chromodomain-helicase-DNA-binding protein Mi-2 homolog

1

0

High-throughput

0.518

High

900621

YAP1
Transcriptional coactivator yorkie

1

20

Small-scale

0.515

High

900623

PTK7
Tyrosine-protein kinase-like otk

1

20

Small-scale

0.515

High

900628

TMTC3
Protein O-mannosyl-transferase Tmtc3

1

3

High-throughput

0.494

High

55222

A1Z995
Sequoia, isoform A

1

2

High-throughput

0.481

High

900631

Q7KUQ6
Limpet, isoform K

1

13

High-throughput

0.481

High

900696

X2JFS5
Uncharacterized protein, isoform C

1

5

High-throughput

0.481

High

55340

A1Z9D7
Low-density lipoprotein receptor-related protein

1

9

Small-scale

0.479

High

56977

A1ZAK9
P-element somatic inhibitor, isoform A

1

6

High-throughput

0.479

High

121003

M9PEK6
Mushroom body defect, isoform L

1

10

Small-scale

0.479

High

233678

O45030
Vang-like protein

1

20

Small-scale

0.479

High

424686

KPC1
Protein kinase C, brain isozyme

1

11

Small-scale

0.479

High

465789

L2GL

1

2

Small-scale

0.479

High

467105

CSK2A
Casein kinase II subunit alpha

1

8

Small-scale

0.479

High

616512

ARM
Armadillo segment polarity protein

1

11

Small-scale

0.479

High

618755

ARRB
Phosrestin-1

1

7

Small-scale

0.479

High

900615

KELC
Ring canal kelch protein [Cleaved into: Kelch short protein]

1

9

Small-scale

0.479

High

900639

Q8IRY0
Dishevelled associated activator of morphogenesis, isoform B

1

5

Small-scale

0.479

High

900668

Q9VRK9
Kinesin-like protein

1

15

Small-scale

0.479

High

900674

FRL
Formin-like protein

1

5

Small-scale

0.479

High

900675

KLHDB
Kelch-like protein diablo

1

9

Small-scale

0.479

High

900667

Q9VR42
Serine/threonine-protein kinase RIO3

1

0

High-throughput

0.458

High

477668

SUHW
Zinc finger protein su(Hw)

1

3

High-throughput

0.457

High

838580

TTKA
Protein tramtrack, alpha isoform

1

18

High-throughput

0.457

High

900633

MICAL
[F-actin]-monooxygenase Mical

1

14

High-throughput

0.457

High

900648

Q95V81
Zinc finger C2H2 protein sequoia

1

2

High-throughput

0.457

High

900683

Q9VWH1
Uncharacterized protein, isoform D

1

6

High-throughput

0.457

High

56929

A1ZAK7
LD35640p

1

6

High-throughput

0.445

High

84961

B7Z126
non-specific serine/threonine protein kinase

1

5

High-throughput

0.445

High

900642

Q8SXP8
TAR DNA-binding protein 43

1

1

High-throughput

0.445

High

900644

ENA
Protein enabled

1

8

High-throughput

0.445

High

900650

Q9BIW6
Brahma-associated protein 111kD

1

4

High-throughput

0.445

High

900657

PPAN
Protein Peter pan

1

1

High-throughput

0.445

High

900685

Q9VYK0
Smrter, isoform D

1

11

High-throughput

0.445

High

900692

Q9W3G1
Uncharacterized protein, isoform A

1

7

High-throughput

0.445

High

900634

Q86P80
CAP, isoform K

1

20

Small-scale

0.439

High

99139

F2FB68
Ensconsin, isoform H

1

20

Small-scale

0.437

High

197441

O18353
CHIP

1

0

High-throughput

0.426

High

638654

MAM
Neurogenic protein mastermind

1

0

High-throughput

0.426

High

900635

MED31
Mediator of RNA polymerase II transcription subunit 31

1

0

High-throughput

0.426

High

900638

INDRA
Zinc finger protein indra

1

0

High-throughput

0.426

High

900656

MED22
Mediator of RNA polymerase II transcription subunit 22

1

0

High-throughput

0.426

High

900670

MED24
Mediator of RNA polymerase II transcription subunit 24

1

0

High-throughput

0.426

High

900677

Q9VVB8
Limpet, isoform A

1

14

High-throughput

0.417

High

900627

Q7K012
Brahma associated protein 55kD

1

10

High-throughput

0.407

High

900643

Q8T4A8
AT07769p

1

1

High-throughput

0.407

High

900664

Q9VNF8
Protein transport protein SEC23

1

3

High-throughput

0.407

High

900682

MED12
Mediator of RNA polymerase II transcription subunit 12

1

1

High-throughput

0.407

High

118364

M9NDS6
Meru, isoform D

2

0

Small-scale

0.306

High

58461

MED8
Mediator of RNA polymerase II transcription subunit 8

2

0

High-throughput

0.298

High

900625

Q7JQT8
LD41464p

2

0

High-throughput

0.298

High

900629

MED29
Mediator of RNA polymerase II transcription subunit 29

2

0

High-throughput

0.298

High

900651

MED10
Mediator of RNA polymerase II transcription subunit 10

2

0

High-throughput

0.298

High

900652

MED7
Mediator of RNA polymerase II transcription subunit 7

2

0

High-throughput

0.298

High

900689

MED14
Mediator of RNA polymerase II transcription subunit 14

2

0

High-throughput

0.298

High

900691

MED16
Mediator of RNA polymerase II transcription subunit 16

2

0

High-throughput

0.298

High

900663

Q9VML8
GH01721p

1

0

High-throughput

0.282

High

900686

Q9VYZ8
GEO08286p1

1

0

High-throughput

0.249

Low

900676

Q9VUV0
RE38335p

1

0

High-throughput

0.238

Low

900617

Q0E996
Eukaryotic translation initiation factor 4 gamma 2

1

0

High-throughput

0.232

Low

900622

Q5BIL9
SD21168p

1

0

High-throughput

0.232

Low

900678

MED19
Mediator of RNA polymerase II transcription subunit 19

1

0

High-throughput

0.232

Low

900620

Q3YNB2
CG11084

1

0

High-throughput

0.198

Low


Service provided by Combinatics, Japan

Last updated: 11Aug2025