HitPredict

Interactor 1: HGS (O14964)
Hepatocyte growth factor-regulated tyrosine kinase substrate (Hrs) (Protein pp110)
Gene: HGS

Interactor 2: LTOR1 (Q6IAA8)
Ragulator complex protein LAMTOR1 (Late endosomal/lysosomal adaptor and MAPK and MTOR activator 1) (Lipid raft adaptor protein p18) (Protein associated with DRMs and endosomes) (p27Kip1-releasing factor from RhoA) (p27RF-Rho)
Gene: LAMTOR1

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	34079125
Identification Methods	proximity labelling technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005764 - lysosome GO:0016197 - endosomal transport GO:0070062 - extracellular exosome GO:0072657 - protein localization to membrane
Homologous interactions	6

Homologous interactions

Color coding for hit scores

	1 777 Hs			1 161
+	Hs
		277077 STAM2_HUMAN (4-521): 4.17e-52: 191: 15.91		LTOR1_HUMAN (1-161): 1.93e-90: 262: 100.00
+	Hs
		1151922 TM1L2_HUMAN (5-448): 6.41e-50: 185: 17.17		LTOR1_HUMAN (1-161): 1.93e-90: 262: 100.00
+	Hs
		1152146 GGA3_HUMAN (6-678): 1.67e-44: 173: 13.14		LTOR1_HUMAN (1-161): 1.93e-90: 262: 100.00
+	Hs
		1151934 ZFY16_HUMAN (137-497): 7.73e-39: 158: 17.76		LTOR1_HUMAN (1-161): 1.93e-90: 262: 100.00
+	Hs
		313549 ZFYV9_HUMAN (155-489): 1.2e-38: 157: 20.63		LTOR1_HUMAN (1-161): 1.93e-90: 262: 100.00
+	Hs
		1152006 RUFY2_HUMAN (1-228): 4.77e-36: 146: 18.03		LTOR1_HUMAN (1-161): 1.93e-90: 262: 100.00