HitPredict

Interactor 1: HGS (O14964)
Hepatocyte growth factor-regulated tyrosine kinase substrate (Hrs) (Protein pp110)
Gene: HGS

Interactor 2: ABI2 (Q9NYB9)
Abl interactor 2 (Abelson interactor 2) (Abi-2) (Abl-binding protein 3) (AblBP3) (Arg-binding protein 1) (ArgBP1)
Gene: ABI2

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.69	0.60	0.646

Property	Details
Experiments	25416956, 29892012
Identification Methods	two hybrid, two hybrid prey pooling approach, two hybrid array, validated two hybrid
Interaction Type	direct interaction, physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005829 - cytosol
Homologous interactions	6

Homologous interactions

Color coding for hit scores

	1 777 Hs			1 513
+	Hs
		277144 STAM2_HUMAN (4-521): 4.17e-52: 191: 15.91		ABI2_HUMAN (1-513): 1.82e-91: 290: 100.00
+	Hs
		159946 HGS_HUMAN (1-777): 5.12e-104: 338: 100.00		GRB2_HUMAN (454-510): 7.13e-18: 84.5: 37.93
+	Hs
		1270628 STAM1_HUMAN (4-172): 1.45e-42: 164: 28.40		ASAP1_HUMAN (65-510): 8.77e-43: 165: 14.66
+	Hs
		272799 TM1L1_HUMAN (5-474): 3.95e-38: 150: 15.19		GRB2_HUMAN (454-510): 7.13e-18: 84.5: 37.93
+	Hs
		203256 ANFY1_HUMAN (156-219): 2.38e-14: 79.3: 50.00		SYNJ1_HUMAN (38-480): 2.57e-33: 137: 12.92
+	Hs
		548761 ANFY1_HUMAN (156-219): 2.38e-14: 79.3: 50.00		VAV_HUMAN (276-513): 8.6e-32: 131: 17.86