HitPredict

Interactor 1: CLGN (O14967)
Calmegin
Gene: CLGN

Interactor 2: MET (P08581)
Hepatocyte growth factor receptor (HGF receptor) (EC 2.7.10.1) (HGF/SF receptor) (Proto-oncogene c-Met) (Scatter factor receptor) (SF receptor) (Tyrosine-protein kinase Met)
Gene: MET

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.47	0.50	0.489

Property	Details
Experiments	33961781
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	-
Homologous interactions	16

Homologous interactions

Color coding for hit scores

	1 610 Hs			1 1390
+	Hs
		441438 CALX_HUMAN (29-610): 0: 729: 56.85		MET_HUMAN (1-1390): 0: 1283: 100.00
+	Hs
		441437 CALR_HUMAN (60-456): 2.91e-129: 387: 36.00		MET_HUMAN (1-1390): 0: 1283: 100.00
+	Hs
		654090 CALX_HUMAN (29-610): 0: 729: 56.85		EPHA3_HUMAN (584-1379): 1.09e-179: 561: 18.13
+	Hs
		654184 CALX_HUMAN (29-610): 0: 729: 56.85		PLXA3_HUMAN (381-1019): 8.58e-111: 388: 17.82
+	Hs
		601462 CALX_HUMAN (29-610): 0: 729: 56.85		FGFR2_HUMAN (1029-1379): 3.01e-105: 355: 33.15
+	Hs
		161056 CLGN_HUMAN (1-610): 0: 804: 100.00		TYRO3_HUMAN (1053-1341): 6.19e-65: 240: 41.67
+	Hs
		161003 CLGN_HUMAN (1-610): 0: 804: 100.00		IGF1R_HUMAN (1084-1337): 2.07e-56: 217: 42.16
+	Hs
		160999 CLGN_HUMAN (1-610): 0: 804: 100.00		INSR_HUMAN (1084-1335): 3.87e-55: 213: 42.11
+	Hs
		654101 CALX_HUMAN (29-610): 0: 729: 56.85		UFO_HUMAN (1078-1333): 5.27e-66: 243: 45.90
+	Hs
		654279 CALX_HUMAN (29-610): 0: 729: 56.85		TYRO3_HUMAN (1053-1341): 6.19e-65: 240: 41.67
+	Hs
		435545 CALX_HUMAN (29-610): 0: 729: 56.85		IGF1R_HUMAN (1084-1337): 2.07e-56: 217: 42.16
+	Hs
		411305 CALX_HUMAN (29-610): 0: 729: 56.85		INSR_HUMAN (1084-1335): 3.87e-55: 213: 42.11
+	Hs
		253453 CALX_HUMAN (29-610): 0: 729: 56.85		PLXA2_HUMAN (380-1069): 6.87e-53: 206: 18.27
+	Hs
		653574 CALR_HUMAN (60-456): 2.91e-129: 387: 36.00		MERTK_HUMAN (1057-1385): 1.56e-67: 249: 40.88
+	Hs
		653493 CALR_HUMAN (60-456): 2.91e-129: 387: 36.00		UFO_HUMAN (1078-1333): 5.27e-66: 243: 45.90
+	Rn
		544766 CALR_RAT (60-456): 5.09e-130: 389: 36.00		INSR_RAT (1084-1335): 3.22e-52: 204: 40.98