HitPredict

Interactor 1: CLGN (O14967)
Calmegin
Gene: CLGN

Interactor 2: NTRK3 (Q16288)
NT-3 growth factor receptor (EC 2.7.10.1) (GP145-TrkC) (Trk-C) (Neurotrophic tyrosine kinase receptor type 3) (TrkC tyrosine kinase)
Gene: NTRK3

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.41	0.50	0.457

Property	Details
Experiments	35384245
Identification Methods	affinity chromatography technology
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	-
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 610 Hs			1 839
+	Hs
		654370 CALX_HUMAN (29-610): 0: 729: 56.85		NTRK3_HUMAN (1-839): 0: 671: 100.00
+	Hs
		160995 CLGN_HUMAN (1-610): 0: 804: 100.00		NTRK1_HUMAN (16-839): 8.14e-173: 520: 46.75
+	Hs
		161008 CLGN_HUMAN (1-610): 0: 804: 100.00		FGFR1_HUMAN (162-838): 5.94e-163: 496: 23.43
+	Hs
		384315 CALX_HUMAN (29-610): 0: 729: 56.85		NTRK1_HUMAN (16-839): 8.14e-173: 520: 46.75
+	Hs
		601462 CALX_HUMAN (29-610): 0: 729: 56.85		FGFR2_HUMAN (203-838): 1.97e-168: 510: 24.89
+	Hs
		507869 CALX_HUMAN (29-610): 0: 729: 56.85		FGFR1_HUMAN (162-838): 5.94e-163: 496: 23.43
+	Hs
		607885 CALX_HUMAN (29-610): 0: 729: 56.85		FGFR4_HUMAN (166-837): 6.43e-152: 466: 24.57
+	Hs
		161002 CLGN_HUMAN (1-610): 0: 804: 100.00		RET_HUMAN (282-837): 1.5e-108: 360: 25.76
+	Hs
		434139 CALX_HUMAN (29-610): 0: 729: 56.85		RET_HUMAN (282-837): 1.5e-108: 360: 25.76
+	Hs
		161053 CLGN_HUMAN (1-610): 0: 804: 100.00		ROR1_HUMAN (509-821): 2.63e-67: 243: 40.50
+	Hs
		161054 CLGN_HUMAN (1-610): 0: 804: 100.00		ROR2_HUMAN (522-828): 2.97e-67: 243: 41.56
+	Hs
		160999 CLGN_HUMAN (1-610): 0: 804: 100.00		INSR_HUMAN (513-824): 1.34e-64: 238: 39.43
+	Hs
		161003 CLGN_HUMAN (1-610): 0: 804: 100.00		IGF1R_HUMAN (513-820): 3.56e-64: 236: 39.16
+	Hs
		654272 CALX_HUMAN (29-610): 0: 729: 56.85		ROR2_HUMAN (522-828): 2.97e-67: 243: 41.56
+	Hs
		411305 CALX_HUMAN (29-610): 0: 729: 56.85		INSR_HUMAN (513-824): 1.34e-64: 238: 39.43
+	Hs
		435545 CALX_HUMAN (29-610): 0: 729: 56.85		IGF1R_HUMAN (513-820): 3.56e-64: 236: 39.16
+	Hs
		654899 CALX_HUMAN (29-610): 0: 729: 56.85		ALK_HUMAN (513-816): 2.78e-59: 222: 39.03
+	Hs
		654302 CALX_HUMAN (29-610): 0: 729: 56.85		PTK7_HUMAN (215-380): 9.02e-12: 71.3: 17.34
+	Rn
		544766 CALR_RAT (60-456): 5.09e-130: 389: 36.00		INSR_RAT (513-824): 3.31e-62: 230: 38.80
+	At
		137905 CALR3_ARATH (53-444): 2.4e-138: 411: 32.32		BRI1_ARATH (22-426): 3.77e-18: 92.1: 12.68