HitPredict

Interactor 1: XPO1 (O14980)
Exportin-1 (Exp1) (Chromosome region maintenance 1 protein homolog)
Gene: XPO1

Interactor 2: RHOB (P62745)
Rho-related GTP-binding protein RhoB (Rho cDNA clone 6) (h6)
Gene: RHOB

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	1.00	0.618

Property	Details
Experiments	34079125
Identification Methods	proximity labelling technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	CRM1_C~Ras, CRM1_repeat~Ras, CRM1_repeat_2~Ras, IBN_N~Ras, Ras~Xpo1
Common GO terms	GO:0005634 - nucleus GO:0005829 - cytosol
Homologous interactions	10

Homologous interactions

Color coding for hit scores

	1 1071 Hs			1 196
+	Hs
		162605 XPO1_HUMAN (1-1071): 0: 1022: 100.00		RAC1_HUMAN (1-196): 2.37e-79: 236: 55.10
+	Hs
		162565 XPO1_HUMAN (1-1071): 0: 1022: 100.00		CDC42_HUMAN (1-196): 1.35e-74: 224: 49.49
+	Hs
		925496 TNPO1_HUMAN (33-1045): 1.81e-132: 425: 13.84		RAC1_HUMAN (1-196): 2.37e-79: 236: 55.10
+	Hs
		207922 XPOT_HUMAN (29-1023): 3.55e-126: 410: 14.85		RAC1_HUMAN (1-196): 2.37e-79: 236: 55.10
+	Hs
		207925 XPOT_HUMAN (29-1023): 3.55e-126: 410: 14.85		RHOG_HUMAN (1-196): 8.84e-76: 227: 51.53
+	Hs
		207919 XPOT_HUMAN (29-1023): 3.55e-126: 410: 14.85		CDC42_HUMAN (1-196): 1.35e-74: 224: 49.49
+	Mm
		983320 XPO7_MOUSE (23-1013): 5.43e-120: 397: 13.01		RAC2_MOUSE (1-196): 6.65e-76: 227: 53.57
+	Hs
		925631 XPO5_HUMAN (26-665): 5.8e-100: 344: 16.12		RAC1_HUMAN (1-196): 2.37e-79: 236: 55.10
+	Hs
		120650 XPO5_HUMAN (26-665): 5.8e-100: 344: 16.12		RHOD_HUMAN (7-182): 3.37e-66: 203: 53.98
+	Hs
		925285 IMB1_HUMAN (27-908): 2.89e-90: 311: 11.32		RAC1_HUMAN (1-196): 2.37e-79: 236: 55.10