Interactor 1: ANM5 (O14744)
Protein arginine N-methyltransferase 5 (PRMT5) (EC 2.1.1.320) (72 kDa ICln-binding protein) (Histone-arginine N-methyltransferase PRMT5) (Jak-binding protein 1) (Shk1 kinase-binding protein 1 homolog) (SKB1 homolog) (SKB1Hs) [Cleaved into: Protein arginine N-methyltransferase 5, N-terminally processed]
Gene: PRMT5

Interactor 2: FBW10 (Q5XX13)
F-box/WD repeat-containing protein 10 (F-box and WD-40 domain-containing protein 10) (Ubiquitin ligase-specificity factor)
Gene: FBXW10

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score Annotation score Interaction score
0.38 1.00 0.618

The method score is based on:

Property Details
Experiments 37450367
Identification Methods affinity chromatography technology
Interaction Type physical association

The annotation score is based on:

Property Details
Interacting Pfam domains PRMT5~WD40, PRMT5_TIM~WD40
Common GO terms GO:0005829 - cytosol
Homologous interactions 9

Homologous interactions

Color coding for hit scores

1 637
Hs

1 1052
+ Hs
+ Hs
+ Hs
+ Hs
+ Ca
+ Hs
+ Hs
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Service provided by Combinatics, Japan

Last updated: 11Aug2025