HitPredict

Interactor 1: TR10B (O14763)
Tumor necrosis factor receptor superfamily member 10B (Death receptor 5) (TNF-related apoptosis-inducing ligand receptor 2) (TRAIL receptor 2) (TRAIL-R2) (CD antigen CD262)
Gene: TNFRSF10B

Interactor 2: CUL3 (Q13618)
Cullin-3 (CUL-3)
Gene: CUL3

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.56	0.60	0.584

Property	Details
Experiments	32313199, 23142077
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005886 - plasma membrane
Homologous interactions	9

Homologous interactions

Color coding for hit scores

	1 440 Hs			1 768
+	Hs
		127676 TR10A_HUMAN (5-440): 6.24e-112: 338: 50.00		CUL3_HUMAN (1-768): 0: 943: 100.00
+	Hs
		163299 TR10B_HUMAN (1-440): 3.46e-136: 400: 100.00		CUL1_HUMAN (18-768): 0: 709: 30.57
+	Hs
		164919 TR10C_HUMAN (33-206): 2.1e-33: 128: 51.14		CUL3_HUMAN (1-768): 0: 943: 100.00
+	Hs
		675023 TNR6_HUMAN (74-185): 4.89e-32: 126: 28.33		CUL3_HUMAN (1-768): 0: 943: 100.00
+	Hs
		1114794 TNR11_HUMAN (62-221): 5.14e-29: 121: 19.19		CUL3_HUMAN (1-768): 0: 943: 100.00
+	Hs
		1113223 LAMA3_HUMAN (79-201): 1.69e-19: 93.9: 18.12		CUL3_HUMAN (1-768): 0: 943: 100.00
+	Hs
		1022536 PGBM_HUMAN (32-267): 1.6e-17: 87.7: 15.53		CUL3_HUMAN (1-768): 0: 943: 100.00
+	Hs
		675024 TNR6_HUMAN (74-185): 4.89e-32: 126: 28.33		CUL4B_HUMAN (5-768): 0: 796: 36.77
+	Hs
		1022537 PGBM_HUMAN (32-267): 1.6e-17: 87.7: 15.53		CUL4A_HUMAN (10-768): 0: 801: 38.32