Interactor 1: AT2A1 (O14983)
Sarcoplasmic/endoplasmic reticulum calcium ATPase 1 (SERCA1) (SR Ca(2+)-ATPase 1) (EC 7.2.2.10) (Calcium pump 1) (Calcium-transporting ATPase sarcoplasmic reticulum type, fast twitch skeletal muscle isoform) (Endoplasmic reticulum class 1/2 Ca(2+) ATPase)
Gene: ATP2A1

Interactor 2: PPLA (P26678)
Cardiac phospholamban (PLB)
Gene: PLN

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.68 1.00 0.827

The method score is based on:

Property Details
Experiments 12032137, 10551848, 11526231
Identification Methods affinity chromatography technology
Interaction Type physical association

The annotation score is based on:

Property Details
Interacting Pfam domains Cation_ATPase_C~Phospholamban
Common GO terms GO:0005739 - mitochondrion
GO:0005789 - endoplasmic reticulum membrane
GO:0006874 - intracellular calcium ion homeostasis
GO:0016020 - membrane
GO:0016529 - sarcoplasmic reticulum
and 3 others

more...

Homologous interactions 3

Homologous interactions

Color coding for hit scores

1 1001
Hs

1 52
+ Oc
+ Mm
+ Hs

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024