Interactor 1: SPTN2 (O15020)
Spectrin beta chain, non-erythrocytic 2 (Beta-III spectrin) (Spinocerebellar ataxia 5 protein)
Gene: SPTBN2

Interactor 2: IQGA1 (P46940)
Ras GTPase-activating-like protein IQGAP1 (p195)
Gene: IQGAP1

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score Annotation score Interaction score
0.47 1.00 0.691

The method score is based on:

Property Details
Experiments 26496610
Identification Methods affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type physical association, association

The annotation score is based on:

Property Details
Interacting Pfam domains CH~CH, CH~Spectrin
Common GO terms GO:0005829 - cytosol
GO:0005886 - plasma membrane
GO:0016324 - apical plasma membrane
GO:0030864 - cortical actin cytoskeleton
GO:0045296 - cadherin binding
and 1 others

more...

Homologous interactions 10

Homologous interactions

Color coding for hit scores

1 2390
Hs

1 1657
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Last updated: 15 Jul 2024