HitPredict

Interactor 1: SPTN2 (O15020)
Spectrin beta chain, non-erythrocytic 2 (Beta-III spectrin) (Spinocerebellar ataxia 5 protein)
Gene: SPTBN2

Interactor 2: ANLN (Q9NQW6)
Anillin
Gene: ANLN

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.56	0.60	0.584

Property	Details
Experiments	31586073, 36526897
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0003779 - actin binding GO:0005829 - cytosol GO:0045296 - cadherin binding
Homologous interactions	10

Homologous interactions

Color coding for hit scores

	1 2390 Hs			1 1124
+	Hs
		963430 SPTB2_HUMAN (3-2390): 0: 712: 61.09		ANLN_HUMAN (1-1124): 0: 1520: 100.00
+	Hs
		211670 ACTN4_HUMAN (56-621): 3.25e-122: 412: 41.70		ANLN_HUMAN (1-1124): 0: 1520: 100.00
+	Hs
		521622 ACTN1_HUMAN (31-766): 7.87e-88: 310: 32.02		ANLN_HUMAN (1-1124): 0: 1520: 100.00
+	Hs
		1045536 SPTN1_HUMAN (279-2273): 5.34e-78: 291: 18.75		ANLN_HUMAN (1-1124): 0: 1520: 100.00
+	Hs
		1068674 PLEC_HUMAN (379-2232): 1.33e-50: 201: 10.46		ANLN_HUMAN (1-1124): 0: 1520: 100.00
+	Hs
		513898 DMD_HUMAN (275-2194): 6.97e-24: 113: 8.91		ANLN_HUMAN (1-1124): 0: 1520: 100.00
+	Hs
		1329040 SPTN4_HUMAN (1248-2382): 2.34e-15: 85.3: 16.21		ANLN_HUMAN (1-1124): 0: 1520: 100.00
+	Hs
		506845 SPTB1_HUMAN (1659-2368): 1.17e-13: 79.5: 12.90		ANLN_HUMAN (1-1124): 0: 1520: 100.00
+	Hs
		974153 DYST_HUMAN (1807-2150): 4.68e-11: 71: 13.35		ANLN_HUMAN (1-1124): 0: 1520: 100.00
+	Dm
		527106 SPTCA_DROME (279-2149): 2.74e-106: 383: 18.91		ANLN_DROME (542-1112): 1.6e-160: 511: 29.84