HitPredict

Interactor 1: SC16A (O15027)
Protein transport protein Sec16A (SEC16 homolog A) (p250)
Gene: SEC16A

Interactor 2: ESR2 (Q92731)
Estrogen receptor beta (ER-beta) (Nuclear receptor subfamily 3 group A member 2)
Gene: ESR2

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.33	0.50	0.407

Property	Details
Experiments	25604459
Identification Methods	tandem affinity purification
Interaction Type	association

Property	Details
Interacting Pfam domains	-
Common GO terms	-
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 2357 Hs			1 530
+	Hs
		164743 SC16A_HUMAN (1-2357): 0: 820: 100.00		ESR1_HUMAN (9-529): 3.58e-138: 413: 44.56
+	Hs
		164761 SC16A_HUMAN (1-2357): 0: 820: 100.00		ANDR_HUMAN (149-407): 8.1e-38: 150: 32.59
+	Hs
		1057780 NCOA6_HUMAN (24-1116): 2.4e-18: 95.1: 8.40		ESR2_HUMAN (1-530): 2.38e-157: 460: 100.00
+	Hs
		1269810 CHD7_HUMAN (21-402): 9.87e-12: 73.4: 10.51		ESR2_HUMAN (1-530): 2.38e-157: 460: 100.00
+	Hs
		377716 SC31B_HUMAN (1365-2123): 8.33e-47: 187: 12.30		GCR_HUMAN (3-495): 1.12e-103: 330: 22.64
+	Hs
		369612 NCOA6_HUMAN (24-1116): 2.4e-18: 95.1: 8.40		ESR1_HUMAN (9-529): 3.58e-138: 413: 44.56
+	Hs
		370263 MINT_HUMAN (3-1242): 2.25e-12: 75.2: 13.32		ESR1_HUMAN (9-529): 3.58e-138: 413: 44.56
+	Hs
		370607 CHD7_HUMAN (21-402): 9.87e-12: 73.4: 10.51		ESR1_HUMAN (9-529): 3.58e-138: 413: 44.56
+	Hs
		587169 NCOA6_HUMAN (24-1116): 2.4e-18: 95.1: 8.40		RXRA_HUMAN (13-502): 1.6e-119: 361: 25.71
+	Hs
		782542 NCOA6_HUMAN (24-1116): 2.4e-18: 95.1: 8.40		HNF4A_HUMAN (94-502): 1.21e-107: 331: 23.30
+	Hs
		377327 NCOA6_HUMAN (24-1116): 2.4e-18: 95.1: 8.40		GCR_HUMAN (3-495): 1.12e-103: 330: 22.64
+	Hs
		487970 NCOA6_HUMAN (24-1116): 2.4e-18: 95.1: 8.40		RARA_HUMAN (52-505): 3.54e-105: 324: 23.74
+	Hs
		1025253 NCOA6_HUMAN (24-1116): 2.4e-18: 95.1: 8.40		NR1H3_HUMAN (65-499): 1.77e-104: 322: 20.97
+	Hs
		874381 NCOA6_HUMAN (24-1116): 2.4e-18: 95.1: 8.40		NR1H2_HUMAN (49-499): 2.78e-103: 319: 20.86
+	Hs
		782640 MINT_HUMAN (3-1242): 2.25e-12: 75.2: 13.32		HNF4A_HUMAN (94-502): 1.21e-107: 331: 23.30
+	Hs
		377624 MINT_HUMAN (3-1242): 2.25e-12: 75.2: 13.32		GCR_HUMAN (3-495): 1.12e-103: 330: 22.64
+	Hs
		782677 CHD7_HUMAN (21-402): 9.87e-12: 73.4: 10.51		HNF4A_HUMAN (94-502): 1.21e-107: 331: 23.30
+	Hs
		377760 CHD7_HUMAN (21-402): 9.87e-12: 73.4: 10.51		GCR_HUMAN (3-495): 1.12e-103: 330: 22.64
+	Hs
		487433 NCOA6_HUMAN (24-1116): 2.4e-18: 95.1: 8.40		ANDR_HUMAN (149-407): 8.1e-38: 150: 32.59
+	Hs
		487803 CHD7_HUMAN (21-402): 9.87e-12: 73.4: 10.51		ANDR_HUMAN (149-407): 8.1e-38: 150: 32.59