HitPredict

Interactor 1: ZBTB5 (O15062)
Zinc finger and BTB domain-containing protein 5
Gene: ZBTB5

Interactor 2: EP300 (Q09472)
Histone acetyltransferase p300 (p300 HAT) (EC 2.3.1.48) (E1A-associated protein p300) (Histone butyryltransferase p300) (EC 2.3.1.-) (Histone crotonyltransferase p300) (EC 2.3.1.-) (Protein 2-hydroxyisobutyryltransferase p300) (EC 2.3.1.-) (Protein lactyltransferas p300) (EC 2.3.1.-) (Protein propionyltransferase p300) (EC 2.3.1.-)
Gene: EP300

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.52	0.60	0.561

Property	Details
Experiments	33051058
Identification Methods	affinity chromatography technology, pull down
Interaction Type	physical association, direct interaction

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0000122 - negative regulation of transcription by RNA polymerase II GO:0000785 - chromatin GO:0005634 - nucleus
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 677 Hs			1 2414
+	Hs
		563593 ZNF24_HUMAN (538-664): 9.75e-54: 190: 32.84		EP300_HUMAN (1-2414): 0: 1113: 100.00
+	Hs
		983966 ZBT16_HUMAN (314-676): 3.62e-37: 149: 15.17		EP300_HUMAN (1-2414): 0: 1113: 100.00
+	Hs
		781351 BCL6_HUMAN (119-571): 4.16e-23: 106: 7.91		EP300_HUMAN (1-2414): 0: 1113: 100.00
+	Hs
		998980 HIC2_HUMAN (254-673): 8.82e-21: 98.8: 13.14		EP300_HUMAN (1-2414): 0: 1113: 100.00
+	Hs
		998634 ZBT17_HUMAN (126-426): 4.29e-20: 97: 4.59		EP300_HUMAN (1-2414): 0: 1113: 100.00
+	Hs
		998963 ZBT8A_HUMAN (613-662): 8.71e-14: 75.9: 46.00		EP300_HUMAN (1-2414): 0: 1113: 100.00
+	Hs
		998827 ZBT49_HUMAN (6-128): 5.83e-13: 74.3: 37.40		EP300_HUMAN (1-2414): 0: 1113: 100.00
+	Hs
		1335865 ZBT20_HUMAN (5-663): 2e-87: 291: 18.09		CHD7_HUMAN (69-452): 4.51e-13: 77.9: 12.02
+	Mm
		57196 Q9QZF3_MOUSE (5-663): 3.09e-90: 298: 18.51		CHD7_MOUSE (1765-2065): 5.9e-10: 67.5: 11.58
+	Hs
		312094 ZBT7A_HUMAN (3-124): 8.29e-19: 92.4: 43.44		BAZ1A_HUMAN (889-1176): 3.58e-51: 202: 21.31
+	Hs
		1055999 ZN460_HUMAN (557-664): 3.2e-25: 112: 21.43		TRI33_HUMAN (604-1201): 1.37e-44: 180: 14.50
+	Hs
		164497 ZN629_HUMAN (105-547): 8.48e-27: 118: 5.10		TRI66_HUMAN (268-1197): 1.08e-40: 168: 12.26
+	Hs
		1357688 KLH20_HUMAN (6-125): 1.77e-14: 79: 39.34		TRI33_HUMAN (604-1201): 1.37e-44: 180: 14.50
+	Hs
		563803 ZNF43_HUMAN (84-323): 1.66e-12: 72.7: 5.83		TRI33_HUMAN (604-1201): 1.37e-44: 180: 14.50
+	Hs
		781369 BCL6_HUMAN (119-571): 4.16e-23: 106: 7.91		BRD3_HUMAN (1055-1159): 9.06e-30: 130: 30.48
+	Mm
		101445 ZBT17_MOUSE (123-546): 1.51e-42: 166: 5.71		F8VPR5_MOUSE (1752-2401): 7.8e-10: 67.1: 12.31
+	Hs
		1056958 ZN251_HUMAN (404-657): 1.43e-33: 138: 14.93		MDC1_HUMAN (455-1061): 8.69e-13: 76.6: 11.82
+	Hs
		631638 KLH20_HUMAN (6-125): 1.77e-14: 79: 39.34		BRD2_HUMAN (1035-1159): 9.57e-30: 131: 31.20
+	Hs
		781408 BCL6_HUMAN (119-571): 4.16e-23: 106: 7.91		CBP_HUMAN (1752-2400): 4.44e-10: 67.9: 13.25
+	Hs
		1057032 KLH20_HUMAN (6-125): 1.77e-14: 79: 39.34		MDC1_HUMAN (455-1061): 8.69e-13: 76.6: 11.82