HitPredict

Interactor 1: LZTR1 (Q8N653)
Leucine-zipper-like transcriptional regulator 1 (LZTR-1)
Gene: LZTR1

Interactor 2: RIT1 (Q92963)
GTP-binding protein Rit1 (EC 3.6.5.2) (Ras-like protein expressed in many tissues) (Ras-like without CAAX protein 1)
Gene: RIT1

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.77	0.50	0.621

Property	Details
Experiments	28514442, 30872527, 33961781
Identification Methods	affinity chromatography technology, pull down, anti tag coimmunoprecipitation
Interaction Type	physical association, direct interaction, association

Property	Details
Interacting Pfam domains	-
Common GO terms	-
Homologous interactions	9

Homologous interactions

Color coding for hit scores

	1 840 Hs			1 219
+	Hs
		1235451 LZTR1_HUMAN (1-840): 0: 613: 100.00		RIT2_HUMAN (8-219): 6.77e-91: 267: 67.93
+	Hs
		348788 LZTR1_HUMAN (1-840): 0: 613: 100.00		RASN_HUMAN (21-184): 3.19e-48: 158: 52.44
+	Hs
		349482 LZTR1_HUMAN (1-840): 0: 613: 100.00		RASH_HUMAN (21-186): 2.02e-48: 158: 51.81
+	Hs
		350348 LZTR1_HUMAN (1-840): 0: 613: 100.00		RASK_HUMAN (21-195): 1.28e-47: 156: 50.29
+	Hs
		214190 SPOP_HUMAN (662-837): 6.69e-62: 215: 31.29		RAB1A_HUMAN (11-218): 4.01e-82: 245: 28.23
+	Hs
		895330 KLDC2_HUMAN (32-264): 9.77e-43: 162: 24.91		RAB2A_HUMAN (17-219): 8.04e-82: 244: 32.35
+	Hs
		214018 SPOP_HUMAN (662-837): 6.69e-62: 215: 31.29		RASH_HUMAN (21-186): 2.02e-48: 158: 51.81
+	Hs
		1120795 KLH12_HUMAN (1-186): 2.59e-28: 122: 18.82		RIT1_HUMAN (1-219): 5e-83: 247: 100.00
+	Hs
		349705 KLHL3_HUMAN (324-575): 1.65e-09: 63.4: 10.67		RASH_HUMAN (21-186): 2.02e-48: 158: 51.81