HitPredict

Interactor 1: BACH1 (O14867)
Transcription regulator protein BACH1 (BTB and CNC homolog 1) (HA2303)
Gene: BACH1

Interactor 2: VHL (P40337)
von Hippel-Lindau disease tumor suppressor (Protein G7) (pVHL)
Gene: VHL

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.44	0.60	0.515

Property	Details
Experiments	32814053
Identification Methods	two hybrid array, two hybrid pooling approach, validated two hybrid
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0000122 - negative regulation of transcription by RNA polymerase II GO:0005634 - nucleus GO:0005654 - nucleoplasm GO:0005829 - cytosol GO:0006355 - regulation of DNA-templated transcription
Homologous interactions	7

Homologous interactions

Color coding for hit scores

	1 736 Hs			1 213
+	Hs
		822722 KLH17_HUMAN (4-338): 7.26e-69: 240: 16.52		VHL_HUMAN (1-213): 3.46e-146: 407: 100.00
+	Hs
		822698 KLH12_HUMAN (14-294): 8.56e-69: 238: 21.40		VHL_HUMAN (1-213): 3.46e-146: 407: 100.00
+	Hs
		822764 ZBT44_HUMAN (18-294): 6.4e-66: 230: 26.96		VHL_HUMAN (1-213): 3.46e-146: 407: 100.00
+	Hs
		822746 KLHL7_HUMAN (20-444): 6.18e-62: 219: 15.85		VHL_HUMAN (1-213): 3.46e-146: 407: 100.00
+	Hs
		822717 KLH10_HUMAN (22-350): 3.91e-61: 218: 14.97		VHL_HUMAN (1-213): 3.46e-146: 407: 100.00
+	Hs
		252982 KLH41_HUMAN (3-412): 1.94e-60: 216: 11.86		VHL_HUMAN (1-213): 3.46e-146: 407: 100.00
+	Hs
		822639 ZBT17_HUMAN (227-490): 5.74e-12: 71.2: 5.63		VHL_HUMAN (1-213): 3.46e-146: 407: 100.00