HitPredict

Interactor 1: VHL (P40337)
von Hippel-Lindau disease tumor suppressor (Protein G7) (pVHL)
Gene: VHL

Interactor 2: KLH10 (Q6JEL2)
Kelch-like protein 10
Gene: KLHL10

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.481

Property	Details
Experiments	35205757
Identification Methods	two hybrid
Interaction Type	direct interaction

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0000902 - cell morphogenesis GO:0016567 - protein ubiquitination GO:0043161 - proteasome-mediated ubiquitin-dependent protein catabolic process GO:1990756 - ubiquitin-like ligase-substrate adaptor activity
Homologous interactions	6

Homologous interactions

Color coding for hit scores

	1 213 Hs			1 608
+	Hs
		822746 VHL_HUMAN (1-213): 3.46e-146: 407: 100.00		KLHL7_HUMAN (14-579): 0: 525: 26.70
+	Hs
		822698 VHL_HUMAN (1-213): 3.46e-146: 407: 100.00		KLH12_HUMAN (19-575): 9.32e-160: 471: 32.14
+	Hs
		822935 VHL_HUMAN (1-213): 3.46e-146: 407: 100.00		NS1BP_HUMAN (253-509): 8.4e-57: 204: 33.85
+	Hs
		822877 VHL_HUMAN (1-213): 3.46e-146: 407: 100.00		KLHL1_HUMAN (260-432): 8.64e-29: 123: 27.72
+	Hs
		822722 VHL_HUMAN (1-213): 3.46e-146: 407: 100.00		KLH17_HUMAN (469-607): 5.45e-27: 117: 25.90
+	Hs
		822762 VHL_HUMAN (1-213): 3.46e-146: 407: 100.00		KLH23_HUMAN (341-574): 5.67e-17: 86.3: 29.63