HitPredict

Interactor 1: NACAD (O15069)
NAC-alpha domain-containing protein 1
Gene: NACAD

Interactor 2: HDAC6 (Q9UBN7)
Histone deacetylase 6 (HD6) (EC 3.5.1.98) (Protein deacetylase HDAC6) (EC 3.5.1.-) (Tubulin-lysine deacetylase HDAC6) (EC 3.5.1.-)
Gene: HDAC6

Species: Homo sapiens

Source: mint

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.43	0.60	0.508

Property	Details
Experiments	21900206
Identification Methods	two hybrid
Interaction Type	direct interaction, physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005737 - cytoplasm
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 1562 Hs			1 1215
+	Hs
		1045227 NACA_HUMAN (1351-1562): 6.2e-30: 121: 60.38		HDAC6_HUMAN (1-1215): 0: 1435: 100.00
+	Hs
		1354160 SRRM2_HUMAN (20-1118): 1.13e-19: 98.9: 9.42		HDAC6_HUMAN (1-1215): 0: 1435: 100.00
+	Dm
		1196991 Q86BH2_DROME (19-1412): 2.22e-34: 147: 9.80		HDAC1_DROME (79-483): 6.2e-159: 486: 19.01
+	Dm
		1276528 Q9NHX6_DROME (19-1412): 3.49e-34: 146: 9.80		HDAC1_DROME (79-483): 6.2e-159: 486: 19.01
+	Hs
		1056921 MDC1_HUMAN (43-905): 3.61e-30: 133: 8.56		HDA10_HUMAN (85-449): 8.19e-152: 473: 53.53
+	Hs
		1038852 NCOR2_HUMAN (8-1489): 5.17e-19: 96.5: 8.37		HDAC1_HUMAN (478-896): 4.05e-166: 503: 20.09
+	Hs
		1270531 SRRM2_HUMAN (20-1118): 1.13e-19: 98.9: 9.42		HDAC2_HUMAN (78-489): 1.04e-157: 481: 21.02
+	Hs
		1270546 NCOR2_HUMAN (8-1489): 5.17e-19: 96.5: 8.37		HDAC2_HUMAN (78-489): 1.04e-157: 481: 21.02
+	Hs
		1038645 CIC_HUMAN (435-1527): 1.1e-10: 69.2: 8.36		HDAC1_HUMAN (478-896): 4.05e-166: 503: 20.09
+	Hs
		880872 NCOR2_HUMAN (8-1489): 5.17e-19: 96.5: 8.37		HDAC4_HUMAN (405-873): 1.97e-147: 474: 36.51
+	Hs
		1282247 NCOR2_HUMAN (8-1489): 5.17e-19: 96.5: 8.37		HDA10_HUMAN (85-449): 8.19e-152: 473: 53.53
+	Hs
		1260208 NCOR2_HUMAN (8-1489): 5.17e-19: 96.5: 8.37		HDAC7_HUMAN (440-891): 6.38e-147: 469: 36.44
+	Hs
		1357907 NCOR2_HUMAN (8-1489): 5.17e-19: 96.5: 8.37		HDAC5_HUMAN (33-471): 3.29e-145: 469: 32.48
+	Mm
		88461 D3Z656_MOUSE (317-985): 7.94e-12: 72.6: 13.17		HDAC4_MOUSE (424-873): 9e-152: 485: 37.16
+	Mm
		1157748 SYNJ1_MOUSE (317-896): 1.58e-11: 71.8: 14.07		HDAC4_MOUSE (424-873): 9e-152: 485: 37.16
+	Mm
		1111987 PRC2C_MOUSE (3-1531): 7.24e-11: 69.6: 7.12		HDAC4_MOUSE (424-873): 9e-152: 485: 37.16
+	Hs
		1270545 PRC2C_HUMAN (26-1552): 5.73e-11: 70: 8.44		HDAC2_HUMAN (78-489): 1.04e-157: 481: 21.02
+	Hs
		1270390 CIC_HUMAN (435-1527): 1.1e-10: 69.2: 8.36		HDAC2_HUMAN (78-489): 1.04e-157: 481: 21.02
+	Hs
		177416 NCOR2_HUMAN (8-1489): 5.17e-19: 96.5: 8.37		HDAC3_HUMAN (479-890): 6.6e-146: 448: 18.29
+	Hs
		1056969 MDC1_HUMAN (43-905): 3.61e-30: 133: 8.56		HDAC8_HUMAN (103-388): 4.42e-19: 92.8: 26.67