HitPredict

Interactor 1: IKKA (O15111)
Inhibitor of nuclear factor kappa-B kinase subunit alpha (I-kappa-B kinase alpha) (IKK-A) (IKK-alpha) (IkBKA) (IkappaB kinase) (EC 2.7.11.10) (Conserved helix-loop-helix ubiquitous kinase) (I-kappa-B kinase 1) (IKK-1) (IKK1) (Nuclear factor NF-kappa-B inhibitor kinase alpha) (NFKBIKA) (Transcription factor 16) (TCF-16)
Gene: CHUK

Interactor 2: TCPQM (Q96SF2)
T-complex protein 1 subunit theta-like 2 (Chaperonin containing T-complex polypeptide 1 subunit 8-like 2)
Gene: CCT8L2

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.47	0.60	0.536

Property	Details
Experiments	33961781
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005524 - ATP binding
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 745 Hs			1 557
+	Hs
		158529 IKKB_HUMAN (1-743): 0: 583: 50.87		TCPQM_HUMAN (1-557): 0: 582: 100.00
+	Hs
		1306728 TBK1_HUMAN (15-726): 2.03e-127: 397: 18.82		TCPH_HUMAN (21-534): 0: 545: 20.83
+	Hs
		843085 TBK1_HUMAN (15-726): 2.03e-127: 397: 18.82		TCPQ_HUMAN (1-532): 0: 535: 31.24
+	Hs
		826932 TBK1_HUMAN (15-726): 2.03e-127: 397: 18.82		TCPG_HUMAN (24-540): 0: 530: 22.89
+	Hs
		842868 IKKE_HUMAN (15-728): 1.47e-123: 387: 19.52		TCPQ_HUMAN (1-532): 0: 535: 31.24
+	Hs
		625579 CDK2_HUMAN (12-312): 1.65e-123: 372: 23.30		TCPH_HUMAN (21-534): 0: 545: 20.83
+	Hs
		826659 IKKE_HUMAN (15-728): 1.47e-123: 387: 19.52		TCPG_HUMAN (24-540): 0: 530: 22.89
+	Hs
		821455 TBK1_HUMAN (15-726): 2.03e-127: 397: 18.82		TCPE_HUMAN (24-528): 5.65e-179: 517: 23.79
+	Hs
		843425 TBK1_HUMAN (15-726): 2.03e-127: 397: 18.82		TCPD_HUMAN (1-521): 1.26e-178: 516: 22.39
+	Hs
		625245 CDK2_HUMAN (12-312): 1.65e-123: 372: 23.30		TCPQ_HUMAN (1-532): 0: 535: 31.24
+	Hs
		1306721 KS6B2_HUMAN (15-419): 1.39e-115: 359: 21.24		TCPH_HUMAN (21-534): 0: 545: 20.83
+	Hs
		821208 IKKE_HUMAN (15-728): 1.47e-123: 387: 19.52		TCPE_HUMAN (24-528): 5.65e-179: 517: 23.79
+	Hs
		843196 IKKE_HUMAN (15-728): 1.47e-123: 387: 19.52		TCPD_HUMAN (1-521): 1.26e-178: 516: 22.39
+	Hs
		625228 CDK2_HUMAN (12-312): 1.65e-123: 372: 23.30		TCPG_HUMAN (24-540): 0: 530: 22.89
+	Hs
		843080 KS6B2_HUMAN (15-419): 1.39e-115: 359: 21.24		TCPQ_HUMAN (1-532): 0: 535: 31.24
+	Hs
		625220 CDK2_HUMAN (12-312): 1.65e-123: 372: 23.30		TCPE_HUMAN (24-528): 5.65e-179: 517: 23.79
+	Hs
		826928 KS6B2_HUMAN (15-419): 1.39e-115: 359: 21.24		TCPG_HUMAN (24-540): 0: 530: 22.89
+	Hs
		625246 CDK2_HUMAN (12-312): 1.65e-123: 372: 23.30		TCPD_HUMAN (1-521): 1.26e-178: 516: 22.39
+	Hs
		821449 KS6B2_HUMAN (15-419): 1.39e-115: 359: 21.24		TCPE_HUMAN (24-528): 5.65e-179: 517: 23.79
+	Hs
		843420 KS6B2_HUMAN (15-419): 1.39e-115: 359: 21.24		TCPD_HUMAN (1-521): 1.26e-178: 516: 22.39