Protein: IL1R2
Interleukin-1 receptor type 2 (IL-1R-2) (IL-1RT-2) (IL-1RT2) (CD121 antigen-like family member B) (CDw121b) (IL-1 type II receptor) (Interleukin-1 receptor beta) (IL-1R-beta) (Interleukin-1 receptor type II) (CD antigen CD121b) [Cleaved into: Interleukin-1 receptor type 2, membrane form (mIL-1R2) (mIL-1RII); Interleukin-1 receptor type 2, soluble form (sIL-1R2) (sIL-1RII)]

Gene: IL1R2
Organism: Homo sapiens
Interactions: 61
UniProt ID: P27930

Gene Ontology (top 5):
GO:0004908 - interleukin-1 receptor activity
GO:0004910 - interleukin-1, type II, blocking receptor activity
GO:0005576 - extracellular region
GO:0005737 - cytoplasm
GO:0005886 - plasma membrane

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

352961

IL1A
Interleukin-1 alpha

3

2

Small-scale

0.843

High

352988

IL1B
Interleukin-1 beta

3

12

Small-scale

0.827

High

655173

SCRIB
Protein scribble homolog

2

8

High-throughput

0.811

High

655199

LRRC1
Leucine-rich repeat-containing protein 1

2

5

High-throughput

0.811

High

577479

IL1RA
Interleukin-1 receptor antagonist protein

2

9

Small-scale

0.754

High

655177

MICB
MHC class I polypeptide-related sequence B

1

2

High-throughput

0.691

High

655203

IL1AP
Interleukin-1 receptor accessory protein

1

14

Small-scale

0.665

High

126515

QSOX1
Sulfhydryl oxidase 1

2

6

High-throughput

0.628

High

301180

RHBT3
Rho-related BTB domain-containing protein 3

2

15

High-throughput

0.628

High

655170

AT2B2
Plasma membrane calcium-transporting ATPase 2

2

1

High-throughput

0.628

High

655181

SE6L2
Seizure 6-like protein 2

2

1

High-throughput

0.628

High

655182

DUSTY
Dual serine/threonine and tyrosine protein kinase

2

5

High-throughput

0.628

High

655183

NLRX1
NLR family member X1

2

2

High-throughput

0.628

High

655184

LONP2
Lon protease homolog 2, peroxisomal

2

1

High-throughput

0.628

High

655190

EXOC6
Exocyst complex component 6

2

1

High-throughput

0.628

High

655191

CIP2A
Protein CIP2A

2

1

High-throughput

0.628

High

655194

RSPRY
RING finger and SPRY domain-containing protein 1

2

5

High-throughput

0.628

High

655208

DYN3
Dynamin-3

2

2

High-throughput

0.628

High

130026

EXOC5
Exocyst complex component 5

2

0

High-throughput

0.602

High

655171

OCRL
Inositol polyphosphate 5-phosphatase OCRL

2

0

High-throughput

0.602

High

655179

ZNG1C
Zinc-regulated GTPase metalloprotein activator 1C

2

0

High-throughput

0.602

High

655186

EXOC8
Exocyst complex component 8

2

0

High-throughput

0.602

High

655189

ZNT5
Proton-coupled zinc antiporter SLC30A5

2

0

High-throughput

0.602

High

655192

EXOC4
Exocyst complex component 4

2

0

High-throughput

0.602

High

655193

NUD16
U8 snoRNA-decapping enzyme

2

0

High-throughput

0.602

High

655197

EXOC2
Exocyst complex component 2

2

0

High-throughput

0.602

High

655200

TBCD
Tubulin-specific chaperone D

2

0

High-throughput

0.602

High

655204

EXOC1
Exocyst complex component 1

2

0

High-throughput

0.602

High

655207

EXOC7
Exocyst complex component 7

2

0

High-throughput

0.602

High

655210

EXC6B
Exocyst complex component 6B

2

1

High-throughput

0.574

High

655211

UBP15
Ubiquitin carboxyl-terminal hydrolase 15

1

4

Small-scale

0.561

High

280210

CBPD
Carboxypeptidase D

1

1

High-throughput

0.536

High

528596

CFTR
Cystic fibrosis transmembrane conductance regulator

1

2

High-throughput

0.536

High

655172

PCDH1
Protocadherin-1

1

6

High-throughput

0.536

High

655209

ITM2B
Integral membrane protein 2B

1

4

High-throughput

0.536

High

172563

GNPAT
Dihydroxyacetone phosphate acyltransferase

1

0

High-throughput

0.513

High

210411

RGS10
Regulator of G-protein signaling 10

1

0

High-throughput

0.513

High

655167

AMRP
Alpha-2-macroglobulin receptor-associated protein

1

0

High-throughput

0.513

High

655176

PDCD2
Programmed cell death protein 2

1

0

High-throughput

0.513

High

655185

CCD50
Coiled-coil domain-containing protein 50

1

0

High-throughput

0.513

High

655198

MYADM
Myeloid-associated differentiation marker

1

0

High-throughput

0.513

High

655169

SYHM
Histidine--tRNA ligase, mitochondrial

1

2

High-throughput

0.489

High

655175

UBE3C
Ubiquitin-protein ligase E3C

1

5

High-throughput

0.489

High

655180

SYAM
Alanine--tRNA ligase, mitochondrial

1

2

High-throughput

0.489

High

655202

AT131
Endoplasmic reticulum transmembrane helix translocase

1

1

High-throughput

0.489

High

655206

RAB21
Ras-related protein Rab-21

1

5

High-throughput

0.489

High

655212

SAR1B
Small COPII coat GTPase SAR1B

1

9

High-throughput

0.489

High

655168

BMI1
Polycomb complex protein BMI-1

1

4

Small-scale

0.437

High

197471

NDUS4
NADH dehydrogenase [ubiquinone] iron-sulfur protein 4, mitochondrial

2

0

High-throughput

0.328

High

237944

EXOC3
Exocyst complex component 3

2

0

High-throughput

0.328

High

272332

MTU1
Mitochondrial tRNA-specific 2-thiouridylase 1

2

0

High-throughput

0.328

High

655187

CISD2
CDGSH iron-sulfur domain-containing protein 2

2

0

High-throughput

0.328

High

655195

MITOK
Mitochondrial potassium channel

2

0

High-throughput

0.328

High

655205

NDUAC
NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 12

2

0

High-throughput

0.328

High

167206

MRPP3
Mitochondrial ribonuclease P catalytic subunit

1

0

High-throughput

0.279

Low

217778

ORC4
Origin recognition complex subunit 4

1

0

High-throughput

0.279

Low

655174

PAF15
PCNA-associated factor

1

0

High-throughput

0.279

Low

655188

ATLA2
Atlastin-2

1

0

High-throughput

0.279

Low

655196

TOPK
Lymphokine-activated killer T-cell-originated protein kinase

1

0

High-throughput

0.279

Low

655201

RTF2
Replication termination factor 2

1

0

High-throughput

0.279

Low

655178

PRR30
Proline-rich protein 30

1

0

High-throughput

0.269

Low


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Last updated: 15 Jul 2024