HitPredict

Interactor 1: IKKB (O14920)
Inhibitor of nuclear factor kappa-B kinase subunit beta (I-kappa-B-kinase beta) (IKK-B) (IKK-beta) (IkBKB) (EC 2.7.11.10) (I-kappa-B kinase 2) (IKK-2) (IKK2) (Nuclear factor NF-kappa-B inhibitor kinase beta) (NFKBIKB) (Serine/threonine protein kinase IKBKB) (EC 2.7.11.1)
Gene: IKBKB

Interactor 2: MYH10 (P35580)
Myosin-10 (Cellular myosin heavy chain, type B) (Myosin heavy chain 10) (Myosin heavy chain, non-muscle IIb) (Non-muscle myosin heavy chain B) (NMMHC-B) (Non-muscle myosin heavy chain IIb) (NMMHC II-b) (NMMHC-IIB)
Gene: MYH10

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	14743216
Identification Methods	tandem affinity purification
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005524 - ATP binding GO:0005634 - nucleus GO:0005737 - cytoplasm GO:0005829 - cytosol GO:0009898 - cytoplasmic side of plasma membrane
Homologous interactions	17

Homologous interactions

Color coding for hit scores

	1 756 Hs			1 1976
+	Hs
		177810 IKKA_HUMAN (1-743): 6.11e-176: 524: 50.40		MYH10_HUMAN (1-1976): 0: 1086: 100.00
+	Hs
		177809 IKKA_HUMAN (1-743): 6.11e-176: 524: 50.40		MYH9_HUMAN (8-1930): 0: 1056: 78.89
+	Hs
		177899 IKKA_HUMAN (1-743): 6.11e-176: 524: 50.40		MYH14_HUMAN (27-1930): 0: 1013: 68.33
+	Hs
		773274 SIK2_HUMAN (6-755): 4.04e-132: 416: 17.41		MYH10_HUMAN (1-1976): 0: 1086: 100.00
+	Hs
		773183 IKKE_HUMAN (15-725): 1.83e-127: 397: 20.35		MYH10_HUMAN (1-1976): 0: 1086: 100.00
+	Hs
		773012 SIK2_HUMAN (6-755): 4.04e-132: 416: 17.41		MYH9_HUMAN (8-1930): 0: 1056: 78.89
+	Hs
		667591 CDK2_HUMAN (12-306): 3.14e-128: 385: 25.08		MYH10_HUMAN (1-1976): 0: 1086: 100.00
+	Hs
		772795 IKKE_HUMAN (15-725): 1.83e-127: 397: 20.35		MYH9_HUMAN (8-1930): 0: 1056: 78.89
+	Hs
		667590 CDK2_HUMAN (12-306): 3.14e-128: 385: 25.08		MYH9_HUMAN (8-1930): 0: 1056: 78.89
+	Hs
		1277781 SIK2_HUMAN (6-755): 4.04e-132: 416: 17.41		MYH14_HUMAN (27-1930): 0: 1013: 68.33
+	Hs
		773251 MARK4_HUMAN (12-337): 3.65e-90: 300: 26.52		MYH10_HUMAN (1-1976): 0: 1086: 100.00
+	Hs
		605578 KAPCA_HUMAN (4-283): 2.85e-90: 288: 27.66		MYH10_HUMAN (1-1976): 0: 1086: 100.00
+	Hs
		772961 MARK4_HUMAN (12-337): 3.65e-90: 300: 26.52		MYH9_HUMAN (8-1930): 0: 1056: 78.89
+	Hs
		605577 KAPCA_HUMAN (4-283): 2.85e-90: 288: 27.66		MYH9_HUMAN (8-1930): 0: 1056: 78.89
+	Hs
		177811 IKKA_HUMAN (1-743): 6.11e-176: 524: 50.40		MYH11_HUMAN (734-1645): 2.37e-45: 183: 16.61
+	Hs
		776855 SIK2_HUMAN (6-755): 4.04e-132: 416: 17.41		MYH11_HUMAN (734-1645): 2.37e-45: 183: 16.61
+	Hs
		563043 CDK2_HUMAN (12-306): 3.14e-128: 385: 25.08		MYH8_HUMAN (1267-1976): 4.33e-43: 176: 17.65