HitPredict

Interactor 1: SCAM1 (O15126)
Secretory carrier-associated membrane protein 1 (Secretory carrier membrane protein 1)
Gene: SCAMP1

Interactor 2: RAB5B (P61020)
Ras-related protein Rab-5B (EC 3.6.5.2)
Gene: RAB5B

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.47	0.60	0.536

Property	Details
Experiments	35271311
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005886 - plasma membrane GO:0006897 - endocytosis GO:0016020 - membrane GO:0030672 - synaptic vesicle membrane
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 338 Hs			1 215
+	Hs
		168381 SCAM1_HUMAN (1-338): 3.96e-161: 455: 100.00		RAB1A_HUMAN (10-213): 8.59e-91: 266: 39.51
+	Hs
		168336 SCAM1_HUMAN (1-338): 3.96e-161: 455: 100.00		RAB5A_HUMAN (1-215): 9.46e-89: 262: 81.86
+	Hs
		168446 SCAM1_HUMAN (1-338): 3.96e-161: 455: 100.00		RAB1B_HUMAN (13-213): 4.44e-89: 262: 39.30
+	Hs
		168358 SCAM1_HUMAN (1-338): 3.96e-161: 455: 100.00		RAB5C_HUMAN (1-215): 7.24e-88: 259: 84.26
+	Hs
		168379 SCAM1_HUMAN (1-338): 3.96e-161: 455: 100.00		RB11A_HUMAN (10-215): 2.59e-86: 255: 38.61
+	Hs
		168431 SCAM1_HUMAN (1-338): 3.96e-161: 455: 100.00		RAB1C_HUMAN (13-213): 9.41e-86: 253: 39.80
+	Hs
		168401 SCAM1_HUMAN (1-338): 3.96e-161: 455: 100.00		RB11B_HUMAN (10-215): 3.73e-85: 252: 39.63
+	Hs
		168526 SCAM2_HUMAN (1-336): 4.88e-141: 404: 53.39		RAB5B_HUMAN (1-215): 4.67e-90: 265: 100.00
+	Hs
		168500 SCAM2_HUMAN (1-336): 4.88e-141: 404: 53.39		RAB5A_HUMAN (1-215): 9.46e-89: 262: 81.86
+	Hs
		725 A0A087WXB0_HUMAN (1-338): 7.27e-144: 410: 92.31		RB11A_HUMAN (10-215): 2.59e-86: 255: 38.61
+	Hs
		168520 SCAM2_HUMAN (1-336): 4.88e-141: 404: 53.39		RAB5C_HUMAN (1-215): 7.24e-88: 259: 84.26
+	Hs
		728 A0A087WXB0_HUMAN (1-338): 7.27e-144: 410: 92.31		RB11B_HUMAN (10-215): 3.73e-85: 252: 39.63
+	Hs
		168529 SCAM2_HUMAN (1-336): 4.88e-141: 404: 53.39		RB11A_HUMAN (10-215): 2.59e-86: 255: 38.61
+	Hs
		168541 SCAM2_HUMAN (1-336): 4.88e-141: 404: 53.39		RB11B_HUMAN (10-215): 3.73e-85: 252: 39.63
+	Hs
		156491 SCAM3_HUMAN (6-315): 1.51e-123: 360: 53.56		RAB1A_HUMAN (10-213): 8.59e-91: 266: 39.51
+	Hs
		156456 SCAM3_HUMAN (6-315): 1.51e-123: 360: 53.56		RAB5A_HUMAN (1-215): 9.46e-89: 262: 81.86
+	Hs
		156476 SCAM3_HUMAN (6-315): 1.51e-123: 360: 53.56		RAB5C_HUMAN (1-215): 7.24e-88: 259: 84.26
+	Hs
		156489 SCAM3_HUMAN (6-315): 1.51e-123: 360: 53.56		RB11A_HUMAN (10-215): 2.59e-86: 255: 38.61
+	Hs
		156506 SCAM3_HUMAN (6-315): 1.51e-123: 360: 53.56		RB11B_HUMAN (10-215): 3.73e-85: 252: 39.63
+	Hs
		1079951 SCAM4_HUMAN (116-323): 1.98e-87: 264: 46.64		RB11B_HUMAN (10-215): 3.73e-85: 252: 39.63