Protein: RPC2
DNA-directed RNA polymerase III subunit RPC2 (RNA polymerase III subunit C2) (EC 2.7.7.6) (C128) (DNA-directed RNA polymerase III 127.6 kDa polypeptide) (DNA-directed RNA polymerase III subunit B)

Gene: RPC2, POLR3B
Organism: Homo sapiens
Interactions: 107
UniProt ID: Q9NW08

Gene Ontology (top 5):
GO:0001056 - RNA polymerase III activity
GO:0003677 - DNA binding
GO:0003899 - DNA-directed 5'-3' RNA polymerase activity
GO:0005654 - nucleoplasm
GO:0005666 - RNA polymerase III complex

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

402757

RPC4
DNA-directed RNA polymerase III subunit RPC4

7

3

Small-scale

0.962

High

1346856

RPC5
DNA-directed RNA polymerase III subunit RPC5

6

3

Small-scale

0.949

High

169970

RPAC1
DNA-directed RNA polymerases I and III subunit RPAC1

5

16

Small-scale

0.925

High

897645

RPAB2
DNA-directed RNA polymerases I, II, and III subunit RPABC2

5

8

Small-scale

0.925

High

1347030

RPC8
DNA-directed RNA polymerase III subunit RPC8

5

11

Small-scale

0.919

High

156073

RPC1
DNA-directed RNA polymerase III subunit RPC1

5

20

Small-scale

0.912

High

921179

RPAB5
DNA-directed RNA polymerases I, II, and III subunit RPABC5

4

9

Small-scale

0.892

High

1347029

RPC10
DNA-directed RNA polymerase III subunit RPC10

4

12

Small-scale

0.892

High

865003

RPAB4
DNA-directed RNA polymerases I, II, and III subunit RPABC4

3

6

Small-scale

0.839

High

1328663

RPC6
DNA-directed RNA polymerase III subunit RPC6

2

2

Small-scale

0.776

High

583603

RPB3
DNA-directed RNA polymerase II subunit RPB3

2

16

High-throughput

0.754

High

583820

RPAB1
DNA-directed RNA polymerases I, II, and III subunit RPABC1

5

9

Small-scale

0.720

High

1347024

UXT
Protein UXT

4

2

High-throughput

0.699

High

1347020

PIHD1
PIH1 domain-containing protein 1

4

2

High-throughput

0.694

High

1273562

TF3B
Transcription factor IIIB 90 kDa subunit

1

5

High-throughput

0.691

High

295683

RMP
Unconventional prefoldin RPB5 interactor 1

4

2

Small-scale

0.686

High

1311825

RPC7L
DNA-directed RNA polymerase III subunit RPC7-like

3

1

High-throughput

0.675

High

738077

PP1G
Serine/threonine-protein phosphatase PP1-gamma catalytic subunit

3

4

High-throughput

0.667

High

1332506

RPAP3
RNA polymerase II-associated protein 3

3

8

High-throughput

0.667

High

1336398

GPN1
GPN-loop GTPase 1

3

13

High-throughput

0.667

High

1347026

PFD2
Prefoldin subunit 2

3

2

High-throughput

0.667

High

387608

P53
Cellular tumor antigen p53

1

1

High-throughput

0.665

High

175542

RPC7
DNA-directed RNA polymerase III subunit RPC7

3

1

Small-scale

0.650

High

270231

RPC9
DNA-directed RNA polymerase III subunit RPC9

3

3

Small-scale

0.650

High

854380

RPAB3
DNA-directed RNA polymerases I, II, and III subunit RPABC3

3

6

Small-scale

0.650

High

1347027

GPN3
GPN-loop GTPase 3

4

13

High-throughput

0.638

High

179852

RPA34
DNA-directed RNA polymerase I subunit RPA34

1

3

High-throughput

0.618

High

317169

RPA1
DNA-directed RNA polymerase I subunit RPA1

1

20

High-throughput

0.618

High

625067

RPB1
DNA-directed RNA polymerase II subunit RPB1

1

20

High-throughput

0.618

High

677029

RPB2
DNA-directed RNA polymerase II subunit RPB2

1

10

High-throughput

0.618

High

738896

RPB9
DNA-directed RNA polymerase II subunit RPB9

1

12

High-throughput

0.618

High

854483

RPB11
DNA-directed RNA polymerase II subunit RPB11-a

1

9

High-throughput

0.618

High

913966

RPB7
DNA-directed RNA polymerase II subunit RPB7

1

11

High-throughput

0.618

High

1326435

RPA49
DNA-directed RNA polymerase I subunit RPA49

1

5

High-throughput

0.618

High

1334514

RPA2
DNA-directed RNA polymerase I subunit RPA2

1

10

High-throughput

0.618

High

1347022

RPA12
DNA-directed RNA polymerase I subunit RPA12

1

13

High-throughput

0.618

High

171686

PFD6
Prefoldin subunit 6

2

4

High-throughput

0.611

High

1327199

MAF1
Repressor of RNA polymerase III transcription MAF1 homolog

2

1

High-throughput

0.611

High

1312891

RPC3
DNA-directed RNA polymerase III subunit RPC3

2

3

Small-scale

0.601

High

228871

PRKN
E3 ubiquitin-protein ligase parkin

2

5

High-throughput

0.584

High

1221376

RPAP2
Putative RNA polymerase II subunit B1 CTD phosphatase RPAP2

2

3

High-throughput

0.584

High

484490

RPAC2
DNA-directed RNA polymerases I and III subunit RPAC2

1

9

High-throughput

0.575

High

1347018

RPC2
DNA-directed RNA polymerase III subunit RPC2

1

10

Small-scale

0.575

High

61768

BDP1
Transcription factor TFIIIB component B'' homolog

1

1

High-throughput

0.536

High

587019

CSK22
Casein kinase II subunit alpha'

1

4

High-throughput

0.536

High

589927

TBP
TATA-box-binding protein

1

4

High-throughput

0.536

High

801424

KI67
Proliferation marker protein Ki-67

1

1

High-throughput

0.536

High

835538

GSK3A
Glycogen synthase kinase-3 alpha

1

4

High-throughput

0.536

High

934514

CSK21
Casein kinase II subunit alpha

1

7

High-throughput

0.536

High

1069533

TEBP
Prostaglandin E synthase 3

1

1

High-throughput

0.536

High

1233230

RYBP
RING1 and YY1-binding protein

1

1

High-throughput

0.536

High

128922

P3C2A
Phosphatidylinositol 4-phosphate 3-kinase C2 domain-containing subunit alpha

1

0

High-throughput

0.513

High

180095

P4HA2
Prolyl 4-hydroxylase subunit alpha-2

1

0

High-throughput

0.513

High

794149

MATR3
Matrin-3

1

0

High-throughput

0.513

High

986859

PSME1
Proteasome activator complex subunit 1

1

0

High-throughput

0.513

High

1330482

DSN1
Kinetochore-associated protein DSN1 homolog

1

0

High-throughput

0.513

High

1347023

UVRAG
UV radiation resistance-associated gene protein

1

0

High-throughput

0.513

High

234587

DSCAM
Cell adhesion molecule DSCAM

1

2

High-throughput

0.494

High

951909

SERF2
Small EDRK-rich factor 2

1

0

High-throughput

0.493

High

796189

MAGA9
Melanoma-associated antigen 9

1

1

High-throughput

0.489

High

1243521

DP13B
DCC-interacting protein 13-beta

1

2

High-throughput

0.489

High

181469

RPB4
DNA-directed RNA polymerase II subunit RPB4

1

3

High-throughput

0.479

High

245008

BRD4
Bromodomain-containing protein 4

1

6

High-throughput

0.479

High

348036

MYC
Myc proto-oncogene protein

1

3

High-throughput

0.479

High

380339

HG2A
HLA class II histocompatibility antigen gamma chain

1

1

High-throughput

0.479

High

553869

RFA2
Replication protein A 32 kDa subunit

1

2

High-throughput

0.479

High

652408

RFA1
Replication protein A 70 kDa DNA-binding subunit

1

3

High-throughput

0.479

High

721598

RFA3
Replication protein A 14 kDa subunit

1

2

High-throughput

0.479

High

853733

IMA5
Importin subunit alpha-5

1

4

High-throughput

0.479

High

906162

PP1A
Serine/threonine-protein phosphatase PP1-alpha catalytic subunit

1

4

High-throughput

0.479

High

909209

UBE2H
Ubiquitin-conjugating enzyme E2 H

1

2

High-throughput

0.479

High

986996

SUH
Recombining binding protein suppressor of hairless

1

2

High-throughput

0.479

High

1029941

TIF1B
Transcription intermediary factor 1-beta

1

2

High-throughput

0.479

High

1035019

FKBP5
Peptidyl-prolyl cis-trans isomerase FKBP5

1

3

High-throughput

0.479

High

1137962

RPRD2
Regulation of nuclear pre-mRNA domain-containing protein 2

1

10

High-throughput

0.479

High

1152543

Q6ICH2
Apolipoprotein B mRNA editing enzyme catalytic subunit 3D

1

2

High-throughput

0.479

High

1171960

TRI67
Tripartite motif-containing protein 67

1

3

High-throughput

0.479

High

1203517

SKAP1
Src kinase-associated phosphoprotein 1

1

3

High-throughput

0.479

High

1299006

RPR1A
Regulation of nuclear pre-mRNA domain-containing protein 1A

1

13

High-throughput

0.479

High

1310525

RIOK1
Serine/threonine-protein kinase RIO1

1

1

High-throughput

0.479

High

1314733

RPAP1
RNA polymerase II-associated protein 1

1

3

High-throughput

0.479

High

1330860

Q9H4D1
Protein kinase

1

3

High-throughput

0.479

High

1331438

PKHA4
Pleckstrin homology domain-containing family A member 4

1

2

High-throughput

0.479

High

1342921

MED4
Mediator of RNA polymerase II transcription subunit 4

1

1

High-throughput

0.479

High

1343454

RPR1B
Regulation of nuclear pre-mRNA domain-containing protein 1B

1

14

High-throughput

0.479

High

1345924

PDRG1
p53 and DNA damage-regulated protein 1

1

2

High-throughput

0.479

High

1347021

TLS1
Splicing factor C9orf78

1

1

High-throughput

0.479

High

1347025

ZRAN1
Ubiquitin thioesterase ZRANB1

1

2

High-throughput

0.479

High

678091

SDHA
Succinate dehydrogenase [ubiquinone] flavoprotein subunit, mitochondrial

1

1

High-throughput

0.470

High

532627

TCTP
Translationally-controlled tumor protein

1

0

High-throughput

0.458

High

622624

RAE1
Rab proteins geranylgeranyltransferase component A 1

1

0

High-throughput

0.458

High

943908

RAE1L
mRNA export factor RAE1

1

0

High-throughput

0.458

High

112045

ASURF
ASNSD1 upstream open reading frame protein

1

1

High-throughput

0.445

High

484419

RPC22
Protein POLR1D, isoform 2

1

1

High-throughput

0.445

High

883652

RIPK4
Receptor-interacting serine/threonine-protein kinase 4

1

3

High-throughput

0.445

High

1284322

ABC3D
DNA dC->dU-editing enzyme APOBEC-3D

1

2

High-throughput

0.445

High

385605

NTRK1
High affinity nerve growth factor receptor

1

2

High-throughput

0.437

High

1067164

BRD3
Bromodomain-containing protein 3

1

8

High-throughput

0.437

High

1150706

GL1AD
DNA-directed RNA polymerase II subunit GRINL1A, isoforms 4/5

1

2

High-throughput

0.437

High

1238716

KRI1
Protein KRI1 homolog

1

1

High-throughput

0.437

High

1298309

DAA10
Dynein axonemal assembly factor 10

1

2

High-throughput

0.437

High

1347019

ASND1
Asparagine synthetase domain-containing protein 1

1

3

High-throughput

0.437

High

1347028

HECD1
E3 ubiquitin-protein ligase HECTD1

1

8

High-throughput

0.437

High

363394

RET4
Retinol-binding protein 4

1

0

High-throughput

0.279

Low

1187615

TRM1L
TRMT1-like protein

1

0

High-throughput

0.279

Low

1188410

ATG9A
Autophagy-related protein 9A

1

0

High-throughput

0.249

Low


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Last updated: 15 Jul 2024