HitPredict

Interactor 1: ARC1B (O15143)
Actin-related protein 2/3 complex subunit 1B (Arp2/3 complex 41 kDa subunit) (p41-ARC)
Gene: ARPC1B

Interactor 2: MYC (P01106)
Myc proto-oncogene protein (Class E basic helix-loop-helix protein 39) (bHLHe39) (Proto-oncogene c-Myc) (Transcription factor p64)
Gene: MYC

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.56	0.60	0.584

Property	Details
Experiments	29467282, 35013218
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 372 Hs			1 454
+	Hs
		347481 ARC1A_HUMAN (1-371): 6.17e-84: 261: 67.83		MYC_HUMAN (1-454): 1.73e-122: 366: 100.00
+	Hs
		346159 LIS1_HUMAN (1-232): 1.28e-57: 194: 13.49		MYC_HUMAN (1-454): 1.73e-122: 366: 100.00
+	Hs
		347550 SNR40_HUMAN (129-370): 1.58e-49: 171: 14.52		MYC_HUMAN (1-454): 1.73e-122: 366: 100.00
+	Hs
		346404 WDR5_HUMAN (173-369): 3.45e-49: 170: 16.08		MYC_HUMAN (1-454): 1.73e-122: 366: 100.00
+	Mm
		348444 FBXW7_MOUSE (1-165): 2.22e-33: 133: 11.98		MYC_MOUSE (1-454): 4.33e-119: 357: 89.01
+	Hs
		282800 CIAO1_HUMAN (142-357): 1.52e-27: 112: 17.78		MYC_HUMAN (1-454): 1.73e-122: 366: 100.00
+	Hs
		348035 NLE1_HUMAN (1-79): 6.06e-21: 95.9: 18.99		MYC_HUMAN (1-454): 1.73e-122: 366: 100.00
+	Hs
		267729 TAF5L_HUMAN (119-364): 1.04e-19: 92.4: 14.18		MYC_HUMAN (1-454): 1.73e-122: 366: 100.00
+	Hs
		379701 SNR40_HUMAN (129-370): 1.58e-49: 171: 14.52		MYCN_HUMAN (12-451): 9.39e-59: 201: 33.40
+	Hs
		379200 WDR5_HUMAN (173-369): 3.45e-49: 170: 16.08		MYCN_HUMAN (12-451): 9.39e-59: 201: 33.40
+	Hs
		607803 WDR5_HUMAN (173-369): 3.45e-49: 170: 16.08		USF1_HUMAN (175-453): 1.02e-39: 146: 18.40
+	Hs
		379170 SEC13_HUMAN (20-297): 6.9e-23: 99.5: 20.46		MYCN_HUMAN (12-451): 9.39e-59: 201: 33.40
+	Hs
		1218698 SNR40_HUMAN (129-370): 1.58e-49: 171: 14.52		MGAP_HUMAN (151-449): 1.22e-27: 118: 17.71
+	Hs
		903353 WDR5_HUMAN (173-369): 3.45e-49: 170: 16.08		MGAP_HUMAN (151-449): 1.22e-27: 118: 17.71
+	Mm
		1112323 FBXW7_MOUSE (1-165): 2.22e-33: 133: 11.98		SRBP2_MOUSE (124-446): 2.23e-37: 147: 13.60
+	Mm
		1257396 FBXW7_MOUSE (1-165): 2.22e-33: 133: 11.98		SRBP1_MOUSE (172-453): 4.45e-35: 140: 16.61
+	Mm
		659344 WDR5_MOUSE (173-369): 3.45e-49: 170: 16.08		MAX_MOUSE (354-454): 3.52e-25: 102: 32.67
+	Hs
		898091 WDR5_HUMAN (173-369): 3.45e-49: 170: 16.08		MAX_HUMAN (354-454): 1.39e-24: 101: 32.67
+	Hs
		267736 TAF5L_HUMAN (119-364): 1.04e-19: 92.4: 14.18		MYCL_HUMAN (29-449): 4.2e-42: 154: 30.11
+	Hs
		267750 TAF5L_HUMAN (119-364): 1.04e-19: 92.4: 14.18		MAX_HUMAN (354-454): 1.39e-24: 101: 32.67