Interactor 1: ARPC3 (O15145)
Actin-related protein 2/3 complex subunit 3 (Arp2/3 complex 21 kDa subunit) (p21-ARC)
Gene: ARPC3

Interactor 2: ARP2 (P61160)
Actin-related protein 2 (Actin-like protein 2)
Gene: ACTR2

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score Annotation score Interaction score
0.94 1.00 0.973

The method score is based on:

Property Details
Experiments 26186194, 28514442, 33961781, 35271311, 37071682, 26496610, 29568061, 24981860, 35235311
Identification Methods affinity chromatography technology, cross-linking study, proximity labelling technology, anti tag coimmunoprecipitation
Interaction Type physical association, association

The annotation score is based on:

Property Details
Interacting Pfam domains Actin~P21-Arc
Common GO terms GO:0005200 - structural constituent of cytoskeleton
GO:0005634 - nucleus
GO:0005829 - cytosol
GO:0005885 - Arp2/3 protein complex
GO:0005925 - focal adhesion
and 6 others

more...

Homologous interactions 5

Homologous interactions

Color coding for hit scores

1 178
Hs

1 394
+ Hs
+ Hs
+ Hs
+ Sp
+ Sc

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024