HitPredict

Interactor 1: BET1 (O15155)
BET1 homolog (hBET1) (Golgi vesicular membrane-trafficking protein p18)
Gene: BET1

Interactor 2: SCFD1 (Q8WVM8)
Sec1 family domain-containing protein 1 (SLY1 homolog) (Sly1p) (Syntaxin-binding protein 1-like 2)
Gene: SCFD1

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.71	0.60	0.657

Property	Details
Experiments	29568061, 33961781, unassigned1655
Identification Methods	affinity chromatography technology, proximity labelling technology, pull down, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0000139 - Golgi membrane GO:0005789 - endoplasmic reticulum membrane GO:0006888 - endoplasmic reticulum to Golgi vesicle-mediated transport
Homologous interactions	11

Homologous interactions

Color coding for hit scores

	1 118 Hs			1 642
+	Hs
		1261652 BET1L_HUMAN (26-115): 3.07e-22: 85.8: 35.87		SCFD1_HUMAN (14-642): 0: 644: 100.00
+	Hs
		235200 STX10_HUMAN (12-97): 4.1e-20: 83.5: 15.12		SCFD1_HUMAN (14-642): 0: 644: 100.00
+	Hs
		212953 STX6_HUMAN (10-97): 1.23e-19: 82.3: 19.32		SCFD1_HUMAN (14-642): 0: 644: 100.00
+	Hs
		1261668 STX8_HUMAN (6-99): 1.08e-09: 55.7: 17.02		SCFD1_HUMAN (14-642): 0: 644: 100.00
+	Dm
		1096659 Q9VVX6_DROME (11-118): 1.25e-27: 99.6: 39.45		SLY1_DROME (13-642): 0: 572: 56.81
+	Hs
		169625 BET1_HUMAN (1-118): 1.93e-45: 144: 100.00		VPS45_HUMAN (38-640): 9.73e-154: 456: 20.66
+	Sc
		605780 BET1_YEAST (13-114): 6.27e-25: 93.5: 22.12		SLY1_YEAST (1-640): 7.62e-163: 483: 31.55
+	Hs
		235214 STX10_HUMAN (12-97): 4.1e-20: 83.5: 15.12		VPS45_HUMAN (38-640): 9.73e-154: 456: 20.66
+	Hs
		213020 STX6_HUMAN (10-97): 1.23e-19: 82.3: 19.32		VPS45_HUMAN (38-640): 9.73e-154: 456: 20.66
+	Hs
		1345175 STX8_HUMAN (6-99): 1.08e-09: 55.7: 17.02		VPS45_HUMAN (38-640): 9.73e-154: 456: 20.66
+	Hs
		212997 STX6_HUMAN (10-97): 1.23e-19: 82.3: 19.32		VP33B_HUMAN (3-639): 2.08e-111: 349: 13.40