Protein: WDFY2
WD repeat and FYVE domain-containing protein 2 (Propeller-FYVE protein) (Prof) (WD40- and FYVE domain-containing protein 2) (Zinc finger FYVE domain-containing protein 22)

Gene: WDFY2
Organism: Homo sapiens
Interactions: 31
UniProt ID: Q96P53

Gene Ontology (top 5):
GO:0001934 - positive regulation of protein phosphorylation
GO:0005769 - early endosome
GO:0008270 - zinc ion binding
GO:0031982 - vesicle
GO:0043231 - intracellular membrane-bounded organelle

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

1399441

RUFY1
RUN and FYVE domain-containing protein 1

3

8

High-throughput

0.861

High

1179239

ERC6L
DNA excision repair protein ERCC-6-like

3

14

High-throughput

0.770

High

1154715

VAMP3
Vesicle-associated membrane protein 3

3

7

High-throughput

0.667

High

354245

ZBED1
E3 SUMO-protein ligase ZBED1

3

0

High-throughput

0.638

High

175759

SR140
U2 snRNP-associated SURP motif-containing protein

3

2

High-throughput

0.609

High

847436

GPDM
Glycerol-3-phosphate dehydrogenase, mitochondrial

3

1

High-throughput

0.609

High

902564

RT29
Small ribosomal subunit protein mS29

3

1

High-throughput

0.609

High

1131220

MESD
LRP chaperone MESD

3

1

High-throughput

0.609

High

1276148

NUP54
Nucleoporin p54

3

7

High-throughput

0.609

High

1295441

C2CD5
C2 domain-containing protein 5

3

2

High-throughput

0.609

High

1311269

CHERP
Calcium homeostasis endoplasmic reticulum protein

3

7

High-throughput

0.609

High

1360082

PALLD
Palladin

3

10

High-throughput

0.609

High

1399442

NUP58
Nucleoporin p58/p45

3

4

High-throughput

0.609

High

1399447

UTP6
U3 small nucleolar RNA-associated protein 6 homolog

3

9

High-throughput

0.609

High

1393992

SPF45
Splicing factor 45

3

7

High-throughput

0.593

High

325586

YIF1A
Protein YIF1A

2

0

High-throughput

0.580

High

1399444

DSN1
Kinetochore-associated protein DSN1 homolog

2

2

High-throughput

0.574

High

1399448

NUDC
Nuclear migration protein nudC

2

14

High-throughput

0.558

High

1139247

AR6P1
ADP-ribosylation factor-like protein 6-interacting protein 1

2

2

High-throughput

0.553

High

1227291

A16L1
Autophagy-related protein 16-1

1

19

High-throughput

0.514

High

1214661

RBM26
RNA-binding protein 26

1

4

High-throughput

0.479

High

1252826

NFXL1
NF-X1-type zinc finger protein NFXL1

1

3

High-throughput

0.479

High

1361288

CTR3
Cationic amino acid transporter 3

4

0

High-throughput

0.360

High

216018

FIBP
Acidic fibroblast growth factor intracellular-binding protein

3

0

High-throughput

0.347

High

1022937

EFNB1
Ephrin-B1

3

0

High-throughput

0.347

High

1389646

MITOK
Mitochondrial potassium channel

3

0

High-throughput

0.347

High

1399443

TDIF1
Deoxynucleotidyltransferase terminal-interacting protein 1

3

0

High-throughput

0.347

High

1399445

MID51
Mitochondrial dynamics protein MIEF1

3

0

High-throughput

0.347

High

469535

SYPH
Synaptophysin

2

0

High-throughput

0.316

High

1399446

RPRM
Protein reprimo

2

0

High-throughput

0.316

High

1108886

PNOC
Prepronociceptin [Cleaved into: Nocistatin; Nociceptin

1

0

High-throughput

0.279

Low


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Last updated: 11Aug2025