HitPredict

Interactor 1: HGS (O14964)
Hepatocyte growth factor-regulated tyrosine kinase substrate (Hrs) (Protein pp110)
Gene: HGS

Interactor 2: LITAF (Q99732)
Lipopolysaccharide-induced tumor necrosis factor-alpha factor (LPS-induced TNF-alpha factor) (Small integral membrane protein of lysosome/late endosome) (p53-induced gene 7 protein)
Gene: LITAF

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.77	0.60	0.683

Property	Details
Experiments	25416956, 25910212, 31515488
Identification Methods	two hybrid, two hybrid prey pooling approach, two hybrid array, validated two hybrid, two hybrid bait and prey pooling approach
Interaction Type	direct interaction, physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0008270 - zinc ion binding
Homologous interactions	3

Homologous interactions

Color coding for hit scores

	1 777 Hs			1 161
+	Hs
		256501 TOM1_HUMAN (5-445): 7.31e-54: 195: 18.54		LITAF_HUMAN (1-161): 1.08e-47: 153: 100.00
+	Hs
		1406905 GGA3_HUMAN (6-678): 5.27e-48: 183: 13.96		LITAF_HUMAN (1-161): 1.08e-47: 153: 100.00
+	Hs
		296554 STAM2_HUMAN (4-521): 1.15e-38: 153: 14.62		LITAF_HUMAN (1-161): 1.08e-47: 153: 100.00