Protein: LITAF
Lipopolysaccharide-induced tumor necrosis factor-alpha factor (LPS-induced TNF-alpha factor) (Small integral membrane protein of lysosome/late endosome) (p53-induced gene 7 protein)

Gene: LITAF
Organism: Homo sapiens
Interactions: 102
UniProt ID: Q99732

Gene Ontology (top 5):
GO:0000139 - Golgi membrane
GO:0000978 - RNA polymerase II cis-regulatory region sequence-specific DNA binding
GO:0001228 - DNA-binding transcription activator activity, RNA polymerase II-specific
GO:0001817 - regulation of cytokine production
GO:0005634 - nucleus

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

861743

NEDD4
E3 ubiquitin-protein ligase NEDD4

5

8

Small-scale

0.726

High

296554

STAM2
Signal transducing adapter molecule 2

5

3

High-throughput

0.725

High

1393435

REEP6
Receptor expression-enhancing protein 6

5

1

High-throughput

0.725

High

1292463

RASF3
Ras association domain-containing protein 3

4

1

High-throughput

0.698

High

1399992

NED4L
E3 ubiquitin-protein ligase NEDD4-like

4

8

Small-scale

0.694

High

347887

BAG3
BAG family molecular chaperone regulator 3

5

0

High-throughput

0.687

High

169728

HGS
Hepatocyte growth factor-regulated tyrosine kinase substrate

3

3

High-throughput

0.683

High

1095770

CACO2
Calcium-binding and coiled-coil domain-containing protein 2

2

1

High-throughput

0.654

High

1406912

UBQL1
Ubiquilin-1

2

5

High-throughput

0.654

High

256501

TOM1
Target of Myb1 membrane trafficking protein

3

3

Small-scale

0.653

High

1334525

RN149
E3 ubiquitin-protein ligase RNF149

3

0

High-throughput

0.638

High

1406911

HPCL4
Hippocalcin-like protein 4

4

9

High-throughput

0.638

High

1406906

WWOX
WW domain-containing oxidoreductase

3

0

Small-scale

0.637

High

131008

HIP1
Huntingtin-interacting protein 1

3

0

High-throughput

0.632

High

507334

UBB
Polyubiquitin-B [Cleaved into: Ubiquitin]

2

4

High-throughput

0.628

High

541656

FGFR1
Fibroblast growth factor receptor 1

2

1

High-throughput

0.628

High

641245

FGFR2
Fibroblast growth factor receptor 2

2

1

High-throughput

0.628

High

658926

PTPRD
Receptor-type tyrosine-protein phosphatase delta

2

1

High-throughput

0.628

High

1129489

PUM1
Pumilio homolog 1

2

1

High-throughput

0.628

High

1394594

ITCH
E3 ubiquitin-protein ligase Itchy homolog

2

8

Small-scale

0.624

High

1386548

OPTN
Optineurin

2

0

High-throughput

0.612

High

329481

EPN2
Epsin-2

2

4

High-throughput

0.606

High

987170

RS27A
Ubiquitin-ribosomal protein eS31 fusion protein

2

4

High-throughput

0.606

High

987456

RL40
Ubiquitin-ribosomal protein eL40 fusion protein

2

3

High-throughput

0.606

High

1137974

TNIP1
TNFAIP3-interacting protein 1

2

2

High-throughput

0.606

High

1244859

KCIP4
Kv channel-interacting protein 4

2

9

High-throughput

0.606

High

1290947

TAXB1
Tax1-binding protein 1

2

1

High-throughput

0.606

High

1396236

TNIP3
TNFAIP3-interacting protein 3

2

2

High-throughput

0.606

High

1406898

RN208
RING finger protein 208

2

2

High-throughput

0.606

High

1406905

GGA3
ADP-ribosylation factor-binding protein GGA3

2

3

High-throughput

0.606

High

1406907

KCIP1
A-type potassium channel modulatory protein KCNIP1

2

9

High-throughput

0.606

High

1406909

UBQL2
Ubiquilin-2

2

5

High-throughput

0.606

High

1406915

EPN1
Epsin-1

2

4

High-throughput

0.606

High

140417

SDCB1
Syntenin-1

2

0

High-throughput

0.602

High

403211

APOB
Apolipoprotein B-100

2

0

High-throughput

0.602

High

787238

BMR1A
Bone morphogenetic protein receptor type-1A

2

0

High-throughput

0.602

High

1278312

LRP10
Low-density lipoprotein receptor-related protein 10

2

0

High-throughput

0.602

High

1406901

CD320
CD320 antigen

2

0

High-throughput

0.602

High

132258

WWP2
NEDD4-like E3 ubiquitin-protein ligase WWP2

2

8

Small-scale

0.601

High

1406892

TS101
Tumor susceptibility gene 101 protein

2

0

Small-scale

0.595

High

1406891

LITAF
Lipopolysaccharide-induced tumor necrosis factor-alpha factor

2

0

Small-scale

0.588

High

270735

N4BP1
NEDD4-binding protein 1

2

0

High-throughput

0.580

High

330287

VENTX
Homeobox protein VENTX

2

0

High-throughput

0.580

High

1039796

CREB5
Cyclic AMP-responsive element-binding protein 5

2

0

High-throughput

0.580

High

1044700

ARI5A
AT-rich interactive domain-containing protein 5A

2

0

High-throughput

0.580

High

1139121

DAZP2
DAZ-associated protein 2

2

0

High-throughput

0.580

High

1156049

ZIC1
Zinc finger protein ZIC 1

2

0

High-throughput

0.580

High

1277223

POGZ
Pogo transposable element with ZNF domain

2

0

High-throughput

0.580

High

1027153

REEP5
Receptor expression-enhancing protein 5

2

1

High-throughput

0.574

High

1348115

PUM2
Pumilio homolog 2

2

1

High-throughput

0.574

High

1406908

HECW2
E3 ubiquitin-protein ligase HECW2

2

8

High-throughput

0.574

High

838249

STAT6
Signal transducer and activator of transcription 6

1

1

Small-scale

0.573

High

789662

HPCL1
Hippocalcin-like protein 1

2

9

High-throughput

0.561

High

962908

NCALD
Neurocalcin-delta

2

9

High-throughput

0.553

High

979422

VISL1
Visinin-like protein 1

2

9

High-throughput

0.553

High

927516

ATX1
Ataxin-1

1

1

High-throughput

0.541

High

517294

ZTRF1
Zinc finger TRAF-type-containing protein 1

2

0

High-throughput

0.528

High

168562

UB2L6
Ubiquitin/ISG15-conjugating enzyme E2 L6

1

1

High-throughput

0.515

High

1331291

RN152
E3 ubiquitin-protein ligase RNF152

1

1

High-throughput

0.515

High

1406686

SMAD5
Mothers against decapentaplegic homolog 5

1

1

High-throughput

0.515

High

1406903

RASF1
Ras association domain-containing protein 1

1

1

High-throughput

0.515

High

1384758

ARL8A
ADP-ribosylation factor-like protein 8A

1

0

High-throughput

0.513

High

562347

LAMP2
Lysosome-associated membrane glycoprotein 2

1

0

High-throughput

0.493

High

1010361

BASP1
Brain acid soluble protein 1

1

0

High-throughput

0.493

High

1014186

CBX1
Chromobox protein homolog 1

1

0

High-throughput

0.493

High

1349652

PPL13
Placental protein 13-like

1

0

High-throughput

0.493

High

1365426

DOCK2
Dedicator of cytokinesis protein 2

1

0

High-throughput

0.493

High

1387097

RN183
E3 ubiquitin-protein ligase RNF183

1

0

High-throughput

0.493

High

1406894

CDCA4
Cell division cycle-associated protein 4

1

0

High-throughput

0.493

High

1406900

CAN10
Calpain-10

1

0

High-throughput

0.493

High

1406902

DDX21
Nucleolar RNA helicase 2

1

0

High-throughput

0.493

High

1406910

AKA11
A-kinase anchor protein 11

1

0

High-throughput

0.493

High

1406913

DAPP1
Dual adapter for phosphotyrosine and 3-phosphotyrosine and 3-phosphoinositide

1

0

High-throughput

0.493

High

1244714

TTC33
Tetratricopeptide repeat protein 33

1

1

High-throughput

0.489

High

1406899

EPN3
Epsin-3

1

4

High-throughput

0.481

High

1119274

CAC1C
Voltage-dependent L-type calcium channel subunit alpha-1C

1

1

Small-scale

0.479

High

1127636

SCN5A
Sodium channel protein type 5 subunit alpha

1

1

Small-scale

0.479

High

1406897

WWP1
NEDD4-like E3 ubiquitin-protein ligase WWP1

1

8

Small-scale

0.479

High

116897

I6L9I8
EPN3 protein

1

4

High-throughput

0.470

High

378174

TNFA
Tumor necrosis factor

1

0

Small-scale

0.458

High

832782

BCL6
B-cell lymphoma 6 protein

1

0

Small-scale

0.458

High

1114113

CUL3
Cullin-3

1

0

High-throughput

0.458

High

1140745

KIF14
Kinesin-like protein KIF14

1

0

High-throughput

0.458

High

1406904

TAB2
TGF-beta-activated kinase 1 and MAP3K7-binding protein 2

1

0

Small-scale

0.458

High

642279

COMT
Catechol O-methyltransferase

1

0

High-throughput

0.438

High

1199667

KLH22
Kelch-like protein 22

1

0

High-throughput

0.426

High

1138944

R3HD1
R3H domain-containing protein 1

2

0

High-throughput

0.328

High

1406914

BCS1
Mitochondrial chaperone BCS1

2

0

High-throughput

0.328

High

884604

SYCC
Cysteine--tRNA ligase, cytoplasmic

1

0

High-throughput

0.279

Low

1141469

ACOX1
Peroxisomal acyl-coenzyme A oxidase 1

1

0

High-throughput

0.279

Low

181759

VILL
Villin-like protein

1

0

High-throughput

0.268

Low

1329410

SAMD3
Sterile alpha motif domain-containing protein 3

1

0

High-throughput

0.268

Low

1341302

COQ8A
Atypical kinase COQ8A, mitochondrial

1

0

High-throughput

0.268

Low

1369132

COR2A
Coronin-2A

1

0

High-throughput

0.268

Low

1393356

T176A
Transmembrane protein 176A

1

0

High-throughput

0.268

Low

1403393

IMP2L
Mitochondrial inner membrane protease subunit 2

1

0

High-throughput

0.268

Low

1406893

Q9BVU5
ARL17 protein

1

0

High-throughput

0.268

Low

1406895

RM04
Large ribosomal subunit protein uL4m

1

0

High-throughput

0.268

Low

1406896

SRCN1
SRC kinase signaling inhibitor 1

1

0

High-throughput

0.268

Low

928748

CACB3
Voltage-dependent L-type calcium channel subunit beta-3

1

0

Small-scale

0.249

Low

1260278

Q75LH2
Ras-associating and dilute domain-containing protein

1

0

High-throughput

0.238

Low


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Last updated: 11Aug2025