HitPredict

Interactor 1: RPAC1 (O15160)
DNA-directed RNA polymerases I and III subunit RPAC1 (DNA-directed RNA polymerase I subunit C) (RNA polymerases I and III subunit AC1) (AC40) (DNA-directed RNA polymerases I and III 40 kDa polypeptide) (RPA40) (RPA39) (RPC40)
Gene: POLR1C

Interactor 2: RPAB5 (P62875)
DNA-directed RNA polymerases I, II, and III subunit RPABC5 (RNA polymerases I, II, and III subunit ABC5) (DNA-directed RNA polymerase III subunit L) (RNA polymerase II 7.6 kDa subunit) (RPB7.6) (RPB10 homolog)
Gene: POLR2L

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.85	1.00	0.927

The method score is based on:

Property	Details
Experiments	33961781, 28514442, 24981860, 35271311, 37071682
Identification Methods	affinity chromatography technology, cross-linking study, anti tag coimmunoprecipitation
Interaction Type	physical association, association

The annotation score is based on:

Property	Details
Interacting Pfam domains	RNA_pol_L~RNA_pol_N
Common GO terms	GO:0001054 - RNA polymerase I activity GO:0001056 - RNA polymerase III activity GO:0003677 - DNA binding GO:0003899 - DNA-directed 5'-3' RNA polymerase activity GO:0005634 - nucleus and 5 others more... GO:0005654 - nucleoplasm GO:0005666 - RNA polymerase III complex GO:0005736 - RNA polymerase I complex GO:0005829 - cytosol GO:0006360 - transcription by RNA polymerase I
Homologous interactions	4

Homologous interactions

Color coding for hit scores

	1	346
Hs

1	67

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024