Protein: PAX8
Paired box protein Pax-8

Gene: PAX8
Organism: Homo sapiens
Interactions: 113
UniProt ID: Q06710

Gene Ontology (top 5):
GO:0000785 - chromatin
GO:0000976 - transcription cis-regulatory region binding
GO:0000978 - RNA polymerase II cis-regulatory region sequence-specific DNA binding
GO:0000981 - DNA-binding transcription factor activity, RNA polymerase II-specific
GO:0001655 - urogenital system development

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

1056598

TLE5
TLE family member 5

3

20

High-throughput

0.653

High

1056599

EP300
Histone acetyltransferase p300

2

20

Small-scale

0.606

High

273992

CREST
Calcium-responsive transactivator

2

16

High-throughput

0.606

High

288298

GCM2
Chorion-specific transcription factor GCMb

2

1

High-throughput

0.606

High

725043

HXC8
Homeobox protein Hox-C8

2

20

High-throughput

0.606

High

725136

HXC9
Homeobox protein Hox-C9

2

20

High-throughput

0.606

High

1025255

CDK3
Cyclin-dependent kinase 3

2

9

High-throughput

0.606

High

1056659

SAE1
SUMO-activating enzyme subunit 1

2

2

High-throughput

0.606

High

1056631

DOK4
Docking protein 4

2

0

High-throughput

0.580

High

170101

AURKA
Aurora kinase A

1

5

Small-scale

0.578

High

473941

NFIC
Nuclear factor 1 C-type

1

20

High-throughput

0.561

High

627957

ANXA7
Annexin A7

1

1

High-throughput

0.561

High

851752

NKX21
Homeobox protein Nkx-2.1

1

18

Small-scale

0.561

High

1056603

SKP2
S-phase kinase-associated protein 2

1

7

Small-scale

0.561

High

1056607

NFIX
Nuclear factor 1 X-type

1

20

High-throughput

0.561

High

1056611

LONF1
LON peptidase N-terminal domain and RING finger protein 1

2

6

High-throughput

0.553

High

177853

IKKA
Inhibitor of nuclear factor kappa-B kinase subunit alpha

1

8

High-throughput

0.541

High

573076

KPYM
Pyruvate kinase PKM

1

1

High-throughput

0.541

High

1037714

PAX5
Paired box protein Pax-5

1

10

High-throughput

0.536

High

1056610

OBF1
POU domain class 2-associating factor 1

1

0

High-throughput

0.518

High

142962

NFIB
Nuclear factor 1 B-type

1

20

High-throughput

0.515

High

442683

RB
Retinoblastoma-associated protein

1

5

Small-scale

0.515

High

1040043

PAX2
Paired box protein Pax-2

1

10

High-throughput

0.515

High

1056600

NFIA
Nuclear factor 1 A-type

1

20

High-throughput

0.515

High

775830

HNF1B
Hepatocyte nuclear factor 1-beta

1

16

High-throughput

0.501

High

1056643

HNRL1
Heterogeneous nuclear ribonucleoprotein U-like protein 1

1

4

High-throughput

0.500

High

138995

BCL9
B-cell CLL/lymphoma 9 protein

1

20

High-throughput

0.479

High

154674

ARI1A
AT-rich interactive domain-containing protein 1A

1

20

High-throughput

0.479

High

161455

KMT2D
Histone-lysine N-methyltransferase 2D

1

20

High-throughput

0.479

High

174344

ZN609
Zinc finger protein 609

1

20

High-throughput

0.479

High

194554

KDM6A
Lysine-specific demethylase 6A

1

9

High-throughput

0.479

High

245615

ZEB2
Zinc finger E-box-binding homeobox 2

1

7

High-throughput

0.479

High

278315

NCOR1
Nuclear receptor corepressor 1

1

20

High-throughput

0.479

High

505550

ATX1L
Ataxin-1-like

1

10

High-throughput

0.479

High

586281

ZEP1
Zinc finger protein 40

1

10

High-throughput

0.479

High

604809

HXB9
Homeobox protein Hox-B9

1

20

High-throughput

0.479

High

833924

HNF4A
Hepatocyte nuclear factor 4-alpha

1

8

Small-scale

0.479

High

879003

NR2C2
Nuclear receptor subfamily 2 group C member 2

1

20

High-throughput

0.479

High

893653

MNX1
Motor neuron and pancreas homeobox protein 1

1

20

High-throughput

0.479

High

903139

SMCA2
SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 2

1

16

High-throughput

0.479

High

927254

ATX1
Ataxin-1

1

10

High-throughput

0.479

High

964590

DCAF7
DDB1- and CUL4-associated factor 7

1

5

High-throughput

0.479

High

1047800

TLE1
Transducin-like enhancer protein 1

1

20

High-throughput

0.479

High

1047954

TLE3
Transducin-like enhancer protein 3

1

20

High-throughput

0.479

High

1048150

TLE4
Transducin-like enhancer protein 4

1

20

High-throughput

0.479

High

1056602

GPS2
G protein pathway suppressor 2

1

4

High-throughput

0.479

High

1056606

MEF2D
Myocyte-specific enhancer factor 2D

1

2

High-throughput

0.479

High

1056608

RBBP5
Retinoblastoma-binding protein 5

1

5

High-throughput

0.479

High

1056609

NCOA2
Nuclear receptor coactivator 2

1

15

High-throughput

0.479

High

1056615

NIPBL
Nipped-B-like protein

1

8

High-throughput

0.479

High

1056617

MDEAS
Mitotic deacetylase-associated SANT domain protein

1

7

High-throughput

0.479

High

1056618

BCOR
BCL-6 corepressor

1

10

High-throughput

0.479

High

1056619

PAXI1
PAX-interacting protein 1

1

19

High-throughput

0.479

High

1056620

PCGF5
Polycomb group RING finger protein 5

1

18

High-throughput

0.479

High

1056621

LDB1
LIM domain-binding protein 1

1

4

High-throughput

0.479

High

1056622

PB1
Protein polybromo-1

1

13

High-throughput

0.479

High

1056623

ZFHX4
Zinc finger homeobox protein 4

1

14

High-throughput

0.479

High

1056625

I2BP1
Interferon regulatory factor 2-binding protein 1

1

2

High-throughput

0.479

High

1056626

FOXP4
Forkhead box protein P4

1

20

High-throughput

0.479

High

1056627

KMT2C
Histone-lysine N-methyltransferase 2C

1

20

High-throughput

0.479

High

1056628

ARI1B
AT-rich interactive domain-containing protein 1B

1

20

High-throughput

0.479

High

1056629

KDM2B
Lysine-specific demethylase 2B

1

7

High-throughput

0.479

High

1056630

MORC4
MORC family CW-type zinc finger protein 4

1

5

High-throughput

0.479

High

1056632

BCL7C
B-cell CLL/lymphoma 7 protein family member C

1

6

High-throughput

0.479

High

1056633

MAML1
Mastermind-like protein 1

1

20

High-throughput

0.479

High

1056634

DPF1
Zinc finger protein neuro-d4

1

20

High-throughput

0.479

High

1056635

REQU
Zinc finger protein ubi-d4

1

20

High-throughput

0.479

High

1056636

CBP
CREB-binding protein

1

20

High-throughput

0.479

High

1056637

SMRD2
SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily D member 2

1

14

High-throughput

0.479

High

1056639

SMRD1
SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily D member 1

1

9

High-throughput

0.479

High

1056640

CIC
Protein capicua homolog

1

20

High-throughput

0.479

High

1056641

PYGO2
Pygopus homolog 2

1

2

High-throughput

0.479

High

1056642

PCGF1
Polycomb group RING finger protein 1

1

14

High-throughput

0.479

High

1056644

SSBP3
Single-stranded DNA-binding protein 3

1

11

High-throughput

0.479

High

1056646

MKRN2
E3 ubiquitin-protein ligase makorin-2

1

2

Small-scale

0.479

High

1056647

TDIF1
Deoxynucleotidyltransferase terminal-interacting protein 1

1

4

High-throughput

0.479

High

1056648

NKX24
Homeobox protein Nkx-2.4

1

20

High-throughput

0.479

High

1056649

FOXP1
Forkhead box protein P1

1

19

High-throughput

0.479

High

1056651

ZN644
Zinc finger protein 644

1

9

High-throughput

0.479

High

1056652

ZN703
Zinc finger protein 703

1

12

High-throughput

0.479

High

1056654

HM20A
High mobility group protein 20A

1

20

High-throughput

0.479

High

1056657

HM20B
SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily E member 1-related

1

20

High-throughput

0.479

High

1056658

CHD7
Chromodomain-helicase-DNA-binding protein 7

1

11

High-throughput

0.479

High

1056660

TRPS1
Zinc finger transcription factor Trps1

1

13

High-throughput

0.479

High

1056662

ZN608
Zinc finger protein 608

1

12

High-throughput

0.479

High

1056663

PRR12
Proline-rich protein 12

1

20

High-throughput

0.479

High

1056664

SATB2
DNA-binding protein SATB2

1

9

High-throughput

0.479

High

1056665

NCOR2
Nuclear receptor corepressor 2

1

19

High-throughput

0.479

High

1056666

NCOA3
Nuclear receptor coactivator 3

1

15

High-throughput

0.479

High

323985

CSTN1
Calsyntenin-1

1

0

High-throughput

0.458

High

487226

PARP1
Poly [ADP-ribose] polymerase 1

1

0

Small-scale

0.458

High

620317

NUCL
Nucleolin

1

0

High-throughput

0.458

High

1056601

ILF2
Interleukin enhancer-binding factor 2

1

0

Small-scale

0.458

High

1056614

RSBN1
Lysine-specific demethylase 9

1

0

High-throughput

0.458

High

1056616

TET2
Methylcytosine dioxygenase TET2

1

0

High-throughput

0.458

High

1056638

TMA16
Translation machinery-associated protein 16

1

0

High-throughput

0.458

High

1056656

LYAR
Cell growth-regulating nucleolar protein

1

0

Small-scale

0.458

High

1056661

FBX3
F-box only protein 3

1

0

Small-scale

0.458

High

1056604

SMAD4
Mothers against decapentaplegic homolog 4

1

5

High-throughput

0.457

High

157273

CTRO
Citron Rho-interacting kinase

1

6

High-throughput

0.457

High

299165

FLOT1
Flotillin-1

1

1

High-throughput

0.457

High

1056605

GSE1
Genetic suppressor element 1

1

4

High-throughput

0.437

High

1056612

QSER1
Glutamine and serine-rich protein 1

1

20

High-throughput

0.437

High

1056613

PRC2B
Protein PRRC2B

1

20

High-throughput

0.437

High

1056624

PRSR1
Proline and serine-rich protein 1

1

13

High-throughput

0.437

High

1056645

UNK
RING finger protein unkempt homolog

1

3

High-throughput

0.437

High

1056650

CPVL
Probable serine carboxypeptidase CPVL

1

1

High-throughput

0.437

High

1056653

FBSL
Fibrosin-1-like protein

1

8

High-throughput

0.437

High

1056655

SERC1
Serine incorporator 1

1

0

High-throughput

0.301

High

1056597

CXCL9
C-X-C motif chemokine 9

1

0

High-throughput

0.282

High

553177

KCRB
Creatine kinase B-type

1

0

High-throughput

0.261

Low

839546

HUTH
Histidine ammonia-lyase

1

0

High-throughput

0.261

Low

428373

RLA2
Large ribosomal subunit protein P2

1

0

High-throughput

0.249

Low


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Last updated: 11Aug2025