HitPredict

Interactor 1: TIF1A (O15164)
Transcription intermediary factor 1-alpha (TIF1-alpha) (EC 2.3.2.27) (E3 ubiquitin-protein ligase TRIM24) (RING finger protein 82) (RING-type E3 ubiquitin transferase TIF1-alpha) (Tripartite motif-containing protein 24)
Gene: TRIM24

Interactor 2: ZN550 (Q7Z398)
Zinc finger protein 550
Gene: ZNF550

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.65	0.60	0.628

Property	Details
Experiments	28514442, 33961781
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 1050 Hs			1 422
+	Hs
		64157 TIF1A_HUMAN (1-1050): 0: 590: 100.00		ZN726_HUMAN (10-422): 3.92e-165: 479: 40.00
+	Hs
		170174 TIF1A_HUMAN (1-1050): 0: 590: 100.00		ZN264_HUMAN (58-398): 3.06e-112: 344: 38.75
+	Hs
		170382 TIF1A_HUMAN (1-1050): 0: 590: 100.00		ZNF74_HUMAN (45-342): 2.48e-92: 293: 30.54
+	Hs
		170365 TIF1A_HUMAN (1-1050): 0: 590: 100.00		ZN460_HUMAN (195-402): 2.94e-70: 233: 55.29
+	Hs
		170463 TIF1A_HUMAN (1-1050): 0: 590: 100.00		ZNF2_HUMAN (54-308): 4.09e-60: 203: 30.98
+	Hs
		170423 TIF1A_HUMAN (1-1050): 0: 590: 100.00		ZN383_HUMAN (42-228): 1.1e-57: 197: 15.46
+	Hs
		170346 TIF1A_HUMAN (1-1050): 0: 590: 100.00		ZN543_HUMAN (53-230): 1.98e-29: 122: 21.35
+	Hs
		1055999 TRI33_HUMAN (53-1045): 1.19e-149: 477: 46.27		ZN460_HUMAN (195-402): 2.94e-70: 233: 55.29
+	Hs
		549240 TRIM1_HUMAN (31-471): 1.64e-70: 252: 14.95		ZN250_HUMAN (78-422): 2.23e-157: 457: 42.54
+	Hs
		64163 TRI39_HUMAN (118-510): 4.03e-61: 219: 10.86		ZN726_HUMAN (10-422): 3.92e-165: 479: 40.00
+	Hs
		563383 TRI39_HUMAN (118-510): 4.03e-61: 219: 10.86		ZNF19_HUMAN (4-422): 9.56e-158: 454: 41.51
+	Hs
		170480 TIF1A_HUMAN (1-1050): 0: 590: 100.00		ZN287_HUMAN (42-124): 3.24e-16: 82.8: 13.25
+	Hs
		170488 TIF1A_HUMAN (1-1050): 0: 590: 100.00		ZN331_HUMAN (44-151): 1.76e-13: 73.6: 12.04
+	Hs
		170449 TIF1A_HUMAN (1-1050): 0: 590: 100.00		ZN333_HUMAN (10-111): 7.97e-12: 69: 33.33
+	Hs
		170388 TIF1A_HUMAN (1-1050): 0: 590: 100.00		ZN484_HUMAN (42-133): 3.77e-09: 60.9: 8.70
+	Hs
		200266 TRI39_HUMAN (118-510): 4.03e-61: 219: 10.86		ZN264_HUMAN (58-398): 3.06e-112: 344: 38.75
+	Hs
		1295375 TRI33_HUMAN (53-1045): 1.19e-149: 477: 46.27		ZN333_HUMAN (10-111): 7.97e-12: 69: 33.33
+	Hs
		1128450 TRI33_HUMAN (53-1045): 1.19e-149: 477: 46.27		ZN484_HUMAN (42-133): 3.77e-09: 60.9: 8.70
+	Hs
		563758 TRI39_HUMAN (118-510): 4.03e-61: 219: 10.86		ZNF26_HUMAN (196-393): 8.32e-65: 218: 53.54
+	Hs
		997546 TRI39_HUMAN (118-510): 4.03e-61: 219: 10.86		ZN543_HUMAN (53-230): 1.98e-29: 122: 21.35