Interactor 1: AXIN1 (O15169)
Axin-1 (Axis inhibition protein 1) (hAxin)
Gene: AXIN1
Interactor 2: GSK3B (P49841)
Glycogen synthase kinase-3 beta (GSK-3 beta) (EC 2.7.11.26) (Serine/threonine-protein kinase GSK3B) (EC 2.7.11.1)
Gene: GSK3B
Species: Homo sapiens
Source: mint
Category: Small-scale
Confidence: High
| Method score | Annotation score | Interaction score |
|---|---|---|
| 0.99 | 1.00 | 0.996 |
The method score is based on:
| Property | Details |
|---|---|
| Experiments | 16293724, 26496610, 26912724, 29045831, 9734785, 28546513, 30181396, 29789528, 12511557, 16199882, 17601533, 18632848, 21242974, 19131971, 21502811, 22270359, 22509369, 20128690, 18593713, 17318175 and 26 others
more... |
| Identification Methods | affinity chromatography technology, two hybrid, pull down, proximity labelling technology, anti tag coimmunoprecipitation, anti bait coimmunoprecipitation, protein kinase assay, tandem affinity purification, fluorescence polarization spectroscopy |
| Interaction Type | physical association, direct interaction, phosphorylation reaction, association |
The annotation score is based on:
| Property | Details |
|---|---|
| Interacting Pfam domains | Pkinase~RGS |
| Common GO terms | GO:0002039 - p53 binding GO:0005634 - nucleus GO:0005737 - cytoplasm GO:0005829 - cytosol GO:0005886 - plasma membrane and 12 others more... |
| Homologous interactions | 8 |
Homologous interactions
Color coding for hit scores 
|
|
|||||||||||||
| + | Hs |   |
|
|||||||||||
| + | Mm | |
|
|||||||||||
| + | Hs | |
 |
|||||||||||
| + | Hs | |
|
|||||||||||
| + | Mm | |
|
|||||||||||
| + | Hs | |
|
|||||||||||
| + | Dm | |
|
|||||||||||
| + | Dm | |
|
|||||||||||
Service provided by Combinatics, Japan
Last updated: 15 Jul 2024
