Protein: HEXA
Beta-hexosaminidase subunit alpha (EC 3.2.1.52) (Beta-N-acetylhexosaminidase subunit alpha) (Hexosaminidase subunit A) (N-acetyl-beta-glucosaminidase subunit alpha)

Gene: HEXA
Organism: Homo sapiens
Interactions: 40
UniProt ID: P06865

Gene Ontology (top 5):
GO:0001501 - skeletal system development
GO:0004563 - beta-N-acetylhexosaminidase activity
GO:0005764 - lysosome
GO:0005829 - cytosol
GO:0005975 - carbohydrate metabolic process

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

449555

HEXB
Beta-hexosaminidase subunit beta

3

1

Small-scale

0.866

High

449579

DHRS4
Dehydrogenase/reductase SDR family member 4

2

0

High-throughput

0.602

High

449556

MPRI
Cation-independent mannose-6-phosphate receptor

1

1

High-throughput

0.536

High

449563

BAG6
Large proline-rich protein BAG6

1

3

High-throughput

0.536

High

449575

SGTB
Small glutamine-rich tetratricopeptide repeat-containing protein beta

1

1

High-throughput

0.536

High

250416

HNRPQ
Heterogeneous nuclear ribonucleoprotein Q

1

0

High-throughput

0.513

High

449557

H2AX
Histone H2AX

1

0

High-throughput

0.513

High

449564

G3BP1
Ras GTPase-activating protein-binding protein 1

1

0

High-throughput

0.513

High

449566

HNRPD
Heterogeneous nuclear ribonucleoprotein D0

1

0

High-throughput

0.513

High

449584

FAN1
Fanconi-associated nuclease 1

1

0

High-throughput

0.513

High

449578

SH23A
SH2 domain-containing protein 3A

1

4

High-throughput

0.489

High

362124

ABL1
Tyrosine-protein kinase ABL1

1

1

High-throughput

0.479

High

440296

FYN
Tyrosine-protein kinase Fyn

1

1

High-throughput

0.479

High

449562

CRK
Adapter molecule crk

1

1

High-throughput

0.479

High

449565

CUL3
Cullin-3

1

1

High-throughput

0.479

High

449580

FBX6
F-box only protein 6

1

2

High-throughput

0.479

High

449581

T106B
Transmembrane protein 106B

1

1

High-throughput

0.479

High

449573

CBP
CREB-binding protein

1

0

Small-scale

0.460

High

240502

PRKN
E3 ubiquitin-protein ligase parkin

1

0

High-throughput

0.458

High

449567

KIF14
Kinesin-like protein KIF14

1

0

High-throughput

0.458

High

449571

CGAS
Cyclic GMP-AMP synthase

1

0

Small-scale

0.458

High

449574

OPTN
Optineurin

1

0

High-throughput

0.458

High

449560

CMA1
Chymase

1

2

High-throughput

0.445

High

217718

TGON2
Trans-Golgi network integral membrane protein 2

1

1

High-throughput

0.437

High

449570

TRI67
Tripartite motif-containing protein 67

1

1

High-throughput

0.437

High

449558

SAP3
Ganglioside GM2 activator

1

0

Small-scale

0.426

High

449559

FPR1
fMet-Leu-Phe receptor

1

0

High-throughput

0.426

High

449569

CYTM
Cystatin-M

1

0

High-throughput

0.426

High

449572

DNS2B
Deoxyribonuclease-2-beta

1

0

High-throughput

0.426

High

449576

AURKB
Aurora kinase B

1

0

High-throughput

0.426

High

143723

WN10B
Protein Wnt-10b

1

1

High-throughput

0.407

High

167430

WNT9A
Protein Wnt-9a

1

1

High-throughput

0.407

High

170619

CLGN
Calmegin

1

2

High-throughput

0.407

High

449568

TERF2
Telomeric repeat-binding factor 2

2

0

High-throughput

0.328

High

449583

UBP22
Ubiquitin carboxyl-terminal hydrolase 22

1

0

High-throughput

0.282

High

449582

PA2GD
Group IID secretory phospholipase A2

1

0

High-throughput

0.279

Low

293070

CD123
Translation initiation factor eIF2 assembly protein

1

0

High-throughput

0.249

Low

449561

RFA3
Replication protein A 14 kDa subunit

1

0

High-throughput

0.249

Low

449585

TRRAP
Transformation/transcription domain-associated protein

1

0

High-throughput

0.249

Low

449577

C170L
Cep170-like protein

1

0

High-throughput

0.232

Low


Service provided by Combinatics, Japan

Last updated: 11Aug2025